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7399-93-1

Basic Information
CAS No.: 7399-93-1
Name: Methyl 6-HydroxypyriMidine-4-carboxylate
Article Data: 6
Molecular Structure:
Molecular Structure of 7399-93-1 (Methyl 6-HydroxypyriMidine-4-carboxylate)
Formula: C6H6N2O3
Molecular Weight: 154.125
Synonyms: 6-Oxo-1,6-dihydro-pyrimidin-4-carbonsaeure-methylester;Methyl6-Hydroxypyrimidine-4-carboxylate;methyl 6-oxo-3,6-dihydropyrimidine-4-carboxylate;6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid methyl ester;Methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate;
Density: 1.39g/cm3
Boiling Point: 263.8°Cat760mmHg
Flash Point: 113.3°C
PSA: 72.05000
LogP: -0.44350
Synthetic route
67-56-1

methanol

6299-87-2

6-oxo-1,6-dihydropyrimidine-4-carboxylic acid

7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

Conditions
ConditionsYield
Stage #1: 6-oxo-1,6-dihydropyrimidine-4-carboxylic acid With chloro-trimethyl-silane In methanol at 20℃; for 8h;
Stage #2: methanol for 0.5h; Heating / reflux;
70%
67-56-1

methanol

7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

Conditions
ConditionsYield
With chloro-trimethyl-silane at 20℃; for 8h;70%
7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

98021-41-1

6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid hydrazide

Conditions
ConditionsYield
With hydrazine In methanol91%
With hydrazine hydrate
7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

98024-63-6

6-oxo-1H-pyrimidine-4-carboxamide

Conditions
ConditionsYield
With ammonia; water
7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

tert-butyl 3-bromo-2,6-dioxopiperidine-1-carboxylate

methyl 1-(1-(tert-butoxycarbonyl)-2,6-dioxopiperidin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxylate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 16h;
7399-93-1

methyl 6-oxo-1,6-dihydropyrimidine-4-carboxylate

1-(1-(tert-butoxycarbonyl)-2,6-dioxopiperidin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 60 °C
2: sodium hydroxide; water / tetrahydrofuran; methanol / 20 h
View Scheme
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    methyl 6-oxo-3H-pyrimidine-4-carboxylateAppearance:Off white to slight yellow solid Storage:Stored in shaded, cool and dry places Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:Handle with cares to avoid damaging the pack

  • Chemical Co.Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

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