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CAS No.: | 936-44-7 |
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Name: | 3-PHENYLPYRROLIDINE |
Article Data: | 24 |
Molecular Structure: | |
Formula: | C10H13N |
Molecular Weight: | 147.22 |
Synonyms: | TIMTEC-BB SBB010168;ASINEX-REAG BAS 03334576;3-PHENYLPYRROLIDINE;(Pyrrolidin-3-yl)benzene |
Density: | 0.988 g/cm3 |
Boiling Point: | 243.36 °C at 760 mmHg |
Flash Point: | 103.142 °C |
Hazard Symbols: | Xi |
Risk Codes: | 22-36-52 |
Safety: | 26 |
PSA: | 12.03000 |
LogP: | 2.09230 |
4-phenyl-2,3-dihydro-1H-pyrrole
3-phenylpyrrolidine
Conditions | Yield |
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With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 3h; | 98% |
Conditions | Yield |
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With ammonium formate; palladium on activated charcoal In methanol | 91% |
With palladium on activated charcoal; ammonium formate In methanol Yield given; | |
With ammonium formate; palladium on activated charcoal In methanol Ambient temperature; |
8-thia-9-azatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene 8,8-dioxide
3-phenylpyrrolidine
Conditions | Yield |
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Stage #1: 8-thia-9-azatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene-8,8-dioxide With ammonia; lithium In tetrahydrofuran at -78℃; for 4.5h; Stage #2: With ammonium chloride In tetrahydrofuran at -78 - 20℃; for 16h; | 90% |
Stage #1: 8-thia-9-azatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene-8,8-dioxide With titanium(IV) isopropylate; chloro-trimethyl-silane; magnesium In tetrahydrofuran at 80 - 100℃; for 15h; Inert atmosphere; Stage #2: With sodium fluoride; sodium hydroxide In tetrahydrofuran; diethyl ether; water at 20℃; for 0.5h; Inert atmosphere; |
tert-butyl 3-phenylpyrrolidine-1-carboxylate
3-phenylpyrrolidine
Conditions | Yield |
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Stage #1: tert-butyl 3-phenylpyrrolidine-1-carboxylate With hydrogenchloride In ethyl acetate for 2h; Stage #2: With potassium carbonate In diethyl ether; water | 87% |
(+-)-phenylsuccinonitrile
3-phenylpyrrolidine
Conditions | Yield |
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With acetic acid; platinum Hydrogenation; |
3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester
3-phenylpyrrolidine
Conditions | Yield |
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With hydrogenchloride In ethanol for 48h; Heating; | |
With hydrogenchloride In methanol Heating; |
3-phenylpyrrolidine
Conditions | Yield |
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With sodium; butan-1-ol |
3-phenylpyrrolidine
Conditions | Yield |
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With sulfuric acid at 18 - 60℃; bei der elektrolytischen Reduktion; |
Conditions | Yield |
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Hydrogenation; |
Conditions | Yield |
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Multi-step reaction with 5 steps 1.1: 85 percent / triethylamine / CH2Cl2 / 3 h / 0 - 20 °C 2.1: 95 percent / di(tricyclohexylphosphine)(benzylidene)ruthenium dichloride / CH2Cl2 / 15 h / 20 °C 3.1: 87 percent / Pd(OAc)2; triphenylphosphine; K2CO3 / dimethylformamide / 15 h / 110 °C 4.1: 93 percent / H2 / Pd/C / ethanol / 15 h / 20 °C 5.1: lithium; NH3 / tetrahydrofuran / 4.5 h / -78 °C 5.2: 90 percent / NH4Cl / tetrahydrofuran / 16 h / -78 - 20 °C View Scheme |
IUPAC Name: 3-phenylpyrrolidine
Empirical Formula: C10H13N
Molecular Weight: 147.2169
Structure of Pyrrolidine, 3-phenyl- (CAS NO.936-44-7):
Index of Refraction: 1.533
Molar Refractivity: 46.23 cm3
Molar Volume: 148.9 cm3
Polarizability: 18.33×10-24cm3
Surface Tension: 36.6 dyne/cm
Density: 0.988 g/cm3
Flash Point: 103.1 °C
Enthalpy of Vaporization: 48.04 kJ/mol
Boiling Point: 243.4 °C at 760 mmHg
Vapour Pressure: 0.0322 mmHg at 25°C
Product Categories: pharmacetical;Pyrrolidine series
Synonyms of Pyrrolidine, 3-phenyl- (CAS NO.936-44-7): 3-Phenylpyrrolidin ; 3-Phenylpyrrolidine
Canonical SMILES: C1CNCC1C2=CC=CC=C2
InChI: InChI=1S/C10H13N/c1-2-4-9(5-3-1)10-6-7-11-8-10/h1-5,10-11H,6-8H2
InChIKey: PRRFFTYUBPGHLE-UHFFFAOYSA-N
Hazard Codes: Xi
Hazard Note: Irritant
HazardClass: IRRITANT