1001648-82-3

Basic information

• Product Name: C₄₄H₅₈FN₄O₈P
• Synonyms: C₄₄H₅₈FN₄O₈P
• CAS NO: 1001648-82-3
• Molecular Weight: 820.939
• Mol File: 1001648-82-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₄H₅₈FN₄O₈P(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₄H₅₈FN₄O₈P(1001648-82-3)
• EPA Substance Registry System: C₄₄H₅₈FN₄O₈P(1001648-82-3)

Safety Data

• Hazardous Substances Data: 1001648-82-3(Hazardous Substances Data)

Upstream product

• 1001648-78-7 1-(3,3-dimethylbutoxy)-N,N,N',N'-tetraisopropylphosphinediamine 
• 159414-98-9 N⁴-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine 

Relevant articles and documents

POLYNUCLEOTIDE CONSTRUCTS HAVING AN AUXILIARY MOIETY NON-BIOREVERSIBLY LINKED TO AN INTERNUCLEOSIDE PHOSPHATE OR PHOSPHOROTHIOATE

The invention features a hybridized polynucleotide construct including a passenger strand, a guide strand loadable into a RISC complex, and one or more auxiliary moieties. At least one of the auxiliary moieties is non-bioreversibly linked to an internucleoside phosphate or phosphorothioate in the passenger strand. The invention further features methods of delivery a polynucleotide construct to a cell and methods of reducing the expression of a protein in a cell. The methods typically involve contacting the cell with the hybridized polynucleotide construct.