159414-98-9

Basic information

• Product Name: 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE
• Synonyms: 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE;N4-ACETYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-CYTIDINE;N4-ACETYL-2'-DEOXY-2'-FLUORO-5'-O-DMT-D-CYTIDINE;N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine;N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine;N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine;DMT-2'-F-Ac-dC;DMT-N4-Ac-2'-F-dC
• CAS NO: 159414-98-9
• Molecular Formula: C₃₂H₃₂FN₃O₇
• Molecular Weight: 589.61
• EINECS: 2017-001-1
• Mol File: 159414-98-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.12±0.20(Predicted)
• CAS DataBase Reference: 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE(159414-98-9)
• EPA Substance Registry System: 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE(159414-98-9)

Safety Data

• Hazardous Substances Data: 159414-98-9(Hazardous Substances Data)

Usage

Description

2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is a chemical compound that is utilized in the field of molecular biology and chemistry. It is a modified nucleoside derivative, specifically a cytidine molecule with a fluorine atom at the 2' position, a dimethoxytrityl group at the 5' position, and an acetyl group at the N4 position. 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is known for its stability and reactivity in various chemical and biological processes.

Uses

Used in Oligonucleotide Synthesis:
2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is used as a building block for the preparation of solid supports for oligonucleotide syntheses. The compound is particularly useful in the synthesis of oligonucleotides that incorporate urea bridges, which are essential for the formation of stable and functional nucleic acid structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is used as a key intermediate in the synthesis of various nucleic acid-based drugs. Its unique chemical properties allow for the development of novel therapeutic agents with improved stability and bioavailability, making it a valuable asset in drug discovery and development.
Used in Research and Development:
2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is also used in research and development for the study of nucleic acid structure, function, and interactions with other biomolecules. Its unique modifications enable researchers to investigate the effects of these modifications on the properties and behavior of nucleic acids, leading to a better understanding of their roles in biological systems and the potential for new therapeutic applications.
Used in Diagnostics:
In the diagnostics industry, 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE can be employed in the development of nucleic acid-based diagnostic tools, such as PCR primers and probes, that offer enhanced performance and specificity due to their modified structures. This can lead to more accurate and reliable diagnostic tests for various diseases and conditions.

Downstream Products

• 1001648-82-3 C₄₄H₅₈FN₄O₈P 
• 1001648-84-5 C₃₉H₄₈FN₄O₈P 
• 1219597-53-1 C₄₇H₆₂FN₄O₁₀PS 
• 1337865-41-4 3'-O-[2-(4-azidomethylphenoxy)acetyl]-5'-O-(4',4''-dimethoxytriphenylmethyl)-N₄-acetyl-2'-deoxy-2'-fluorocytidine