1003013-93-1

Basic information

• Product Name: (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride
• Synonyms: (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride
• CAS NO: 1003013-93-1
• Molecular Weight: 363.262
• Mol File: 1003013-93-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride(1003013-93-1)
• EPA Substance Registry System: (R)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionyl chloride(1003013-93-1)

Safety Data

• Hazardous Substances Data: 1003013-93-1(Hazardous Substances Data)

Upstream product

• 625114-43-4 (2R)-2-(3-chloro-4-methanesulfonylphenyl)-3-[(1R)-3-oxocyclopentyl]propanoic acid 

Downstream Products

• 625114-41-2 Piragliatin 
• 1003013-97-5 (R)-N-{1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazol-3-yl}-2-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-propionamide 

Relevant articles and documents

Pyrazole glucokinase activators

Disclosed herein are pyrazole glucokinase activators of the formula (I) useful for the treatment of metabolic diseases and disorders, preferably diabetes mellitus.

CRYSTALLINE ISOPROPANOL SOLVATE OF GLUCOKINASE ACTIVATOR

Provided is a crystalline IPA solvate of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)- 3-((R)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide as a glucokinase activator which increases insulin secretion in the treatment of, for example, type II diabetes.