1003845-08-6

Basic information

• Product Name: 2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER
• Synonyms: 2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER;2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;2-dioxaborolan-2-yl)pyriMidine;2-ChloropyriMidin-5-ylboronic acid pinacol ester
• CAS NO: 1003845-08-6
• Molecular Formula: C₁₀H₁₄BClN₂O₂
• Molecular Weight: 258.50964
• Mol File: 1003845-08-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 65.0 to 69.0 °C
• Boiling Point: 369.1±15.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.19±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Refrigerated.
• PKA: -1.68±0.22(Predicted)
• CAS DataBase Reference: 2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER(1003845-08-6)
• EPA Substance Registry System: 2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER(1003845-08-6)

Safety Data

• Hazardous Substances Data: 1003845-08-6(Hazardous Substances Data)

Usage

InChI:InChI=1S/C10H14BClN2O2/c1-9(2)10(3,4)16-11(15-9)7-5-13-8(12)14-6-7/h5-6H,1-4H3

Upstream product

• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 1003845-06-4 (2-chloropyrimidin-5-yl)boronic acid 
• 1722-12-9 2-chloropyrimidine 
• 73183-34-3 bis(pinacol)diborane 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 1195-66-0 2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 1003847-58-2 C₂₃H₃₉BN₄O₄ 
• 402960-38-7 5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrimidin-2-ylamine 
• 1202805-27-3 1-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]piperidin-4-one 
• 69034-12-4 2-chloro-5-(trifluoromethyl)pyrimidine 

Relevant articles and documents

Understanding the Activation of Air-Stable Ir(COD)(Phen)Cl Precatalyst for C-H Borylation of Aromatics and Heteroaromatics

A newly developed robust catalyst [Ir(COD)(Phen)Cl] (A) was used for the C-H borylation of three dozen aromatics and heteroaromatics with excellent yield and selectivity. Activation of the catalyst was identified by the use of catalytic amounts of water, alcohols, etc., when B2pin2 was used in noncoordinating solvents, while for THF catalytic use of HBpin was required. The results were on par with the in situ based expensive system [Ir(OMe)(COD)]2/dtbbpy or Me4Phen.

CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

A condensed cyclic compound represented by Formula 1 and an organic light-emitting device including the same.

ORGANIC COMPOUNDS

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.