1007561-82-1

Basic information

• Product Name: 3-hydroxy-1-phenylsulfonyl-2,3-dihydroindole
• Synonyms: 3-hydroxy-1-phenylsulfonyl-2,3-dihydroindole
• CAS NO: 1007561-82-1
• Molecular Weight: 275.328
• Mol File: 1007561-82-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-1-phenylsulfonyl-2,3-dihydroindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-1-phenylsulfonyl-2,3-dihydroindole(1007561-82-1)
• EPA Substance Registry System: 3-hydroxy-1-phenylsulfonyl-2,3-dihydroindole(1007561-82-1)

Safety Data

• Hazardous Substances Data: 1007561-82-1(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 40899-71-6 1-benzenesulfonylindole 
• 6814-64-8 methylenedimethyl sulfurane 
• 151721-32-3 N-benzenesulfonyl-o-aminobenzaldehyde 

Downstream Products

• 40899-71-6 1-benzenesulfonylindole 

Relevant articles and documents

Metal-free borylative dearomatization of indoles: Exploring the divergent reactivity of aminoborane C-H borylation catalysts

While the dearomatization of indoles by carbon-boron bond forming reactions is new and quite promising, they are so far mainly metal-catalyzed. Here, we establish the use of metal-free catalysts in promoting such reactions in an atom-efficient way. The in situ generated ambiphilic aminoborane catalyst (1-Pip-2-BH2-C6H4)2 (Pip = piperidyl) promotes borylative dearomatization of various 1-arylsulfonyl indoles with pinacolborane in a syn addition fashion, with H and Bpin groups added respectively to the 2 and 3 positions of indoles. Catalysis proceeds with good to excellent conversion and essentially with complete regio- and diastereoselectivity. From mechanistic insights and DFT computations, we realized and established that prototypical boranes can also catalyze this borylative dearomatization.

Heterocycles from ylides. Part X.Synthesis of 3-hydroxy-2,3-dihydroindoles by a domino reaction

A domino reaction between 2-N-phenylsulfonylaminobenzaldehyde (1) and sulfonium ylides (2) leads to 3-hydroxy-2,3-dihydroindoles (3) whose structure was confirmed on the basis of analytical and spectroscopic data.