100868-46-0

Basic information

• Product Name: 3,5-Dichloro-4-Picoline
• Synonyms: 3,5-Dichloro-4-Picoline;3,5-Dichloro-4-methylpyridine;Pyridine,3,5-dichloro-4-Methyl-
• CAS NO: 100868-46-0
• Molecular Formula: C₆H₅Cl₂N
• Molecular Weight: 162.0166
• EINECS: -0
• Product Categories: pharmacetical;Pyridine
• Mol File: 100868-46-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 49 °C
• Boiling Point: 203.615 °C at 760 mmHg
• Flash Point: 95.8 °C
• Appearance: /
• Density: 1.319g/cm³
• Vapor Pressure: 0.392mmHg at 25°C
• Refractive Index: 1.547
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.62±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dichloro-4-Picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-4-Picoline(100868-46-0)
• EPA Substance Registry System: 3,5-Dichloro-4-Picoline(100868-46-0)

Safety Data

• Hazardous Substances Data: 100868-46-0(Hazardous Substances Data)

Usage

General Description

3,5-Dichloro-4-Picoline is a chemical compound with the molecular formula C6H4Cl2N. It is a member of the picoline family, which are derivatives of pyridine. 3,5-Dichloro-4-Picoline is a colorless to light yellow liquid with a strong odor and is primarily used as an intermediate in the production of pesticides, pharmaceuticals, and other organic compounds. It is also used as a solvent and in the manufacture of dyes and pigments. 3,5-Dichloro-4-Picoline is primarily produced through chemical synthesis and is considered to be toxic if ingested or inhaled, with potential harmful effects on the respiratory and central nervous systems.

InChI:InChI=1/C6H5Cl2N/c1-4-5(7)2-9-3-6(4)8/h2-3H,1H3

Upstream product

• 108-89-4 picoline 
• 38113-08-5 3,4-dihydro-2-methoxy-4-methyl-2H-pyran 
• 917-64-6 methyl magnesium iodide 
• 153463-65-1 3,5-dichloropyridine-4-carbonitrile 
• 2457-47-8 3,5-dichloropyridine 
• 144-55-8 sodium hydrogencarbonate 
• 74-88-4 methyl iodide 
• 917-54-4 methyllithium 

Downstream Products

• 159088-33-2 4-[2-(3-Cyclopentyloxy-4-methoxyphenyl)-2-hydroxyethyl]-3,5-dichloropyridine 
• 1001909-97-2 1-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(3,5-dichloro-1-pyridin-4-yl)ethanone 

Relevant articles and documents

A SUBSTITUTED TETRAHYDROISOQUINOLINE DERIVATIVE AS A D1 POSITIVE ALLOSTERIC MODULATOR

The present invention relates to compounds according to formula (I), which are a positive allosteric modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.

Ester derivatives as phosphodiesterase inhibitors

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are new ester derivatives, methods of preparing such compounds, compositions containing them and therapeutic use thereof

Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridynyl alkylene alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.