101084-64-4

Basic information

• Product Name: 2-methyl-4,5-dinitro-benzoic acid
• Synonyms: 2-methyl-4,5-dinitro-benzoic acid
• CAS NO: 101084-64-4
• Molecular Weight: 226.145
• Mol File: 101084-64-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-methyl-4,5-dinitro-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4,5-dinitro-benzoic acid(101084-64-4)
• EPA Substance Registry System: 2-methyl-4,5-dinitro-benzoic acid(101084-64-4)

Safety Data

• Hazardous Substances Data: 101084-64-4(Hazardous Substances Data)

Upstream product

• 1975-51-5 2-methyl-4-nitrobenzoic acid 
• 89001-53-6 2-cyano-5-nitrotoluene 

Downstream Products

• 408335-80-8 4-Hydroxy-2-methyl-5-nitro-benzoesaeure 
• 90348-28-0 4,5-dinitrophthalic acid 
• 857009-14-4 2-methyl-4,5-dinitro-benzoyl chloride 
• 86139-87-9 4,5-diamino-2-methylbenzoic acid 
• 101420-71-7 2-methyl-4,5-dinitro-benzoic acid amide 
• 89939-49-1 4-amino-5-nitrophthalic acid 
• 856806-22-9 5-nitro-4-hydroxyphthalic acid 
• 408339-12-8 4-methoxy-5-nitro-phthalic acid 
• 89939-56-0 4-Hydroxylamino-5-nitro-phthalsaeure 
• 55366-00-2 methyl 4-methoxy-2-methyl-5-nitro-benzoate 
• 1441174-39-5 methyl 2-(bromomethyl)-4-methoxy-5-nitro-benzoate 
• 84869-39-6 7-carboxylumichrome 

Relevant articles and documents

PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS

Photoactive probes and probe systems for detecting biological interactions are described. The photoactive probes include probes that combine both photocleavable and photoreactive moieties. The photoactive probe systems can include a first probe comprising a photocatalytic group and a second probe comprising a group that can act as a substrate for the reaction catalyzed by the photocatalytic group. The probes and probe systems can also include groups that can specifically bind to a binding partner on a biological entity of interest and a detectable group or a precursor thereof. The probes and probe systems can detect spatiotemporal interactions of proteins or cells. In some embodiments, the interactions can be detected in live cells. Also described are methods of detecting the biological interactions.

Cyclic-fused ASK1 inhibitor and application thereof

The invention relates to a cyclic-fused ASK1 inhibitor and application thereof, and particularly to a compound shown in formula (I), a pharmacologically acceptable salt and ester thereof, and a stereisomer thereof. The invention further relates to a preparation method of the compound, a pharmaceutic preparation and a pharmaceutical composition containing the compound. The compound of the inventionis capable of effectively inhibiting phosphorylation of amino acid of ASK1, and inhibiting the activation of the ASK1, thereby can be used for treating and/or preventing ASK1-mediated diseases and related diseases.

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

Compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for t