101315-56-4

Basic information

• Product Name: 3-(4-bromophenyl)quinolin-2(1H)-one
• Synonyms: 3-(4-bromophenyl)quinolin-2(1H)-one
• CAS NO: 101315-56-4
• Molecular Weight: 300.154
• Mol File: 101315-56-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-(4-bromophenyl)quinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenyl)quinolin-2(1H)-one(101315-56-4)
• EPA Substance Registry System: 3-(4-bromophenyl)quinolin-2(1H)-one(101315-56-4)

Safety Data

• Hazardous Substances Data: 101315-56-4(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 589-17-3 p-bromobenzyl chloride 
• 552-89-6 2-nitro-benzaldehyde 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 615-43-0 2-iodophenylamine 
• 144-62-7 oxalic acid 
• 10113-39-0 N-formyl-2-iodoaniline 
• 1200688-13-6 C₁₅H₁₀BrNO 
• 33768-43-3 N-(2-formylphenyl)benzamide 
• 62551-73-9 2-oxo-2-(4-bromophenyl)acetyl chloride 
• 78133-84-3 (2-aminobenzyl)triphenylphosphonium bromide 
• 7099-87-8 4-bromophenylglyoxylic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 101315-52-0 2-(4-Bromphenylglyoxyloylamino)benzyltriphenylphosphoniumbromid 

Relevant articles and documents

Supported Palladium Nanoparticles-Catalyzed Synthesis of 3-Substituted 2-Quinolones from 2-Iodoanilines and Alkynes Using Oxalic Acid as C1 Source

3-Aryl/alkyl-2-quinolones were synthesized employing microwave assisted multicomponent reaction of 2-iodoanilines, terminal alkynes and oxalic acid dihydrate ((CO2H)2 ? 2H2O) under polystyrene supported palladium (Pd@PS) nanoparticles-catalyzed conditions. The use of a heterogeneous palladium catalyst was explored first time for 2-quinolone synthesis involving carbonylation reaction employing (CO2H)2 ? 2H2O as a solid and bench stable carbon monoxide (CO) source. The reaction exhibited good substrate generality for 2-iodoanilines and alkynes with wide functional group tolerance and good regio-selectivity. The ligand free operation, recyclability of heterogeneous Pd@PS catalyst and use of bench stable C1 source are the invaluable merits of the protocol. (Figure presented.).

Synthesis of 3-substituted quinolin-2(1H)-ones via the cyclization of o-alkynylisocyanobenzenes

A facile synthesis of various functionalized 3-substituted quinolin-2(1H)-ones through Ag(i) nitrate-catalyzed cyclization of o-alkynylisocyanobenzenes is described. The reaction allows rapid and convenient access to 3-substituted quinolin-2(1H)-one scaffolds in moderate to good yields.

Base catalysed intermolecular cyclisation of N-protected o-amino benzaldehyde/acetophenone with phosphorus/sulphur based allenes: facile synthesis of substituted quinolines

Reaction of N-Bz protected o-aminobenzaldehyde or acetophenone with allenylphosphonates in the presence of a simple base leads to quaternary carbon substituted phosphono-quinolines which undergo thermal rearrangement to O-phosphorylated quinolines. The pr