1013330-27-2

Basic information

• Product Name: 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride
• Synonyms: 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride;4-Phenyl-1-(phenylmethyl)-4-piperidinecarboxylic acid hydrochloride (1:1)
• CAS NO: 1013330-27-2
• Molecular Formula: C₁₉H₂₁NO₂*ClH
• Molecular Weight: 331.83648
• Product Categories: Aromatics;Heterocycles;Intermediates;Aromatics, Heterocycles, Intermediates
• Mol File: 1013330-27-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride(1013330-27-2)
• EPA Substance Registry System: 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride(1013330-27-2)

Safety Data

• Hazardous Substances Data: 1013330-27-2(Hazardous Substances Data)

Usage

Description

1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride is a disubstituted piperidinecarboxylic acid derivative characterized by the presence of a benzyl and phenyl group attached to the piperidine ring. 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride exhibits unique structural features that make it a valuable intermediate in the synthesis of various pharmaceutical agents.

Uses

Used in Pharmaceutical Industry:
1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride is used as a key intermediate in the synthesis of calcium channel blockers for the treatment of cardiovascular diseases. Its unique structural features allow for the development of drugs that can effectively regulate calcium ion flow in cardiac and vascular smooth muscle cells, leading to the relaxation of these muscles and the alleviation of symptoms associated with hypertension, angina, and certain arrhythmias.
In the preparation of calcium channel blockers, 1-Benzyl-4-phenyl-4-piperidinecarboxylic Acid Hydrochloride serves as a crucial building block, enabling the creation of diverse chemical entities with potential therapeutic benefits. Its versatility in chemical reactions allows for the synthesis of a wide range of calcium channel blockers with varying selectivity, potency, and pharmacokinetic properties, catering to the specific needs of patients with different cardiovascular conditions.

Upstream product

• 56243-25-5 1-benzyl-4-cyano-4-phenylpiperidine 

Downstream Products

• 95703-61-0 1-(1-benzyl-4-phenyl-piperidine-4-carbonyl)-piperidine 
• 1013330-13-6 (1-benzyl-4-phenylpiperidin-4-yl)(3,5-dimethylpiperazin-1-yl)methanone 

Relevant articles and documents

DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS

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