101646-02-0 Usage
Description
3-Chloro-4-fluoro-5-nitrobenzotrifluoride is a chemical compound with the molecular formula C7H2ClF3N2O2. It is characterized by the presence of a chloro, fluoro, and nitro group attached to a benzene ring, with three trifluoromethyl groups attached to the same ring. 3-CHLORO-4-FLUORO-5-NITROBENZOTRIFLUORIDE has potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-Chloro-4-fluoro-5-nitrobenzotrifluoride is used as a pyrolyl-tRNA synthetase inhibitor for the development of drugs targeting abnormal intracellular signaling pathways. Its ability to inhibit these pathways makes it a potential candidate for treating various diseases, including nervous and mental disorders and inflammatory diseases, that are caused by such abnormalities.
Used in Research Applications:
3-Chloro-4-fluoro-5-nitrobenzotrifluoride can be used as a research tool to study the mechanisms of action of pyrolyl-tRNA synthetase inhibitors and their effects on cellular processes. This can help in understanding the role of these enzymes in disease development and progression, as well as in the discovery of new therapeutic targets and drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 101646-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,6,4 and 6 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 101646-02:
(8*1)+(7*0)+(6*1)+(5*6)+(4*4)+(3*6)+(2*0)+(1*2)=80
80 % 10 = 0
So 101646-02-0 is a valid CAS Registry Number.
101646-02-0Relevant articles and documents
1-phenyl-6-one-pyrimidine derivatives
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, (2008/06/13)
A compound of formula (I): STR1 wherein R1 and R2 are independently selected from hydrogen, halogen, haloalkyl, alkoxy or nitro, provided that R1 and R2 are not both nitro; R3 and R4 are independently selected from hydrogen, halogen, alkyl or cycloalkyl; R5 is halogen, nitro, haloalkyl, haloalkoxy or --S(O)n R10 ; R6 is halogen, nitro, haloalkyl, haloalkoxy or --S(O)n R10 ; R7 is hydrogen, halogen, hydroxyalkyl, cyano, nitro, alkoxy, --S(O)n R10, NR11 R12, haloalkyl or formyl; R8 is hydrogen, halogen, NR11 R12, alkyl, cycloalkyl or S(O)n R10 ; and R9 is oxygen or sulphur; where n is 0, 1 or 2; and R10 is alkyl, haloalkyl or cycloalkyl; and R11 and R12 are independently selected from hydrogen, alkyl or cycloalkyl or R11 and R12 together with the nitrogen to which they are attached form a heterocyclic group; provided that when R5 is trifluoromethyl at least one of the following applies: (i) R1 or R2 is haloalkyl or alkoxy; (ii) R3 or R4 are alkyl or cycloalkyl; (iii) R6 is haloalkoxy, nitro or --S(O)n R10 ; (iv) R7 is nitro, hydroxyakyl, alkoxy, S(O)n R10, NR11 R12, formyl or haloalkyl; (v) R8 is other than hydrogen; (vi) R9 is sulphur; and further provided that (a) R1, R2, R3 and R4 are not all fluorine and (b) when R5 is chlorine, R1 and R2 are both halogen.