657-02-3 Usage
Description
3,4-DICHLORO-5-NITROBENZOTRIFLUORIDE is an organic compound characterized by the presence of two chlorine atoms at the 3rd and 4th positions, a nitro group at the 5th position, and three fluorine atoms attached to the benzene ring. 3,4-DICHLORO-5-NITROBENZOTRIFLUORIDE is known for its chemical reactivity and is commonly used as an intermediate in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
3,4-DICHLORO-5-NITROBENZOTRIFLUORIDE is used as a chemical intermediate for the preparation of 2,6-Dichloro-4-trifluoromethylphenylamine, which is an important compound in the synthesis of certain pharmaceuticals. The unique structure of 3,4-DICHLORO-5-NITROBENZOTRIFLUORIDE allows for the formation of specific chemical bonds that are crucial for the development of these pharmaceuticals.
Used in Chemical Synthesis:
3,4-DICHLORO-5-NITROBENZOTRIFLUORIDE is used as a reagent in various chemical reactions, such as substitution, addition, and elimination reactions. Its presence of electron-withdrawing groups makes it a versatile compound for the synthesis of a wide range of organic compounds, including dyes, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 657-02-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 657-02:
(5*6)+(4*5)+(3*7)+(2*0)+(1*2)=73
73 % 10 = 3
So 657-02-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H2Cl2F3NO2/c8-4-1-3(7(10,11)12)2-5(6(4)9)13(14)15/h1-2H
657-02-3Relevant articles and documents
Design and synthesis of new mitochondrial cytotoxin N-thiadiazolylanilines that inhibit tumor cell growth
Hori, Hitoshi,Noguchi, Naoto,Yokoyama, Hideakira,Ise, Hirohiko,Jin, Cheng-Zhe,Kasai, Soko,Goto, Takatsugu,Taira, Zenei
, p. 247 - 253 (2007/10/03)
New N-thiadiazolylanilines were designed and synthesized to develop mitochondrial cytotoxins superior to SF 6847. The mitochondrial cytotoxin N-thiadiazolylanilines, TX-108 and TX-109, inhibited EMT6/KU mammary sarcoma cell growth at a low micromolar concentration. Their inhibitory activities were parallel to their mitochondrial cytotoxicity, such as uncoupling oxidative phosphorylation and inhibiting ATP synthesis. This report also supports the notion that the inhibition of tumor cell growth of inhibitor of protein tyrosine kinase AG17, which is identical to SF 6847, may be due to its mitochondrial cytotoxicity.
Herbicidal 4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers
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, (2008/06/13)
The herbicidal-4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.
Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers
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, (2008/06/13)
Salts of compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and compositions containing these salts exhibit herbicidal activity.