10166-54-8 Usage
Description
1-methyltetrahydro-2(1H)-pyrimidinone (SALTDATA: FREE) is a thiourea derivative with a unique chemical structure that has been identified for its potential applications in various fields. It is characterized by its ability to induce differentiation in murine erythroleukemia cells, which makes it a promising candidate for further research and development in the pharmaceutical and biotechnology industries.
Uses
Used in Pharmaceutical Industry:
1-methyltetrahydro-2(1H)-pyrimidinone (SALTDATA: FREE) is used as an inducer of murine erythroleukemia differentiation for the development of novel therapeutic strategies against cancer. Its ability to induce differentiation in cancer cells suggests that it may play a role in the treatment of certain types of leukemia and other malignancies by promoting the maturation of cancer cells, thereby reducing their proliferative capacity and potential for metastasis.
Additionally, due to its unique chemical properties, 1-methyltetrahydro-2(1H)-pyrimidinone (SALTDATA: FREE) may also be explored for its potential applications in other areas of pharmaceutical research, such as the development of new drugs targeting various diseases and conditions.
Used in Biotechnology Industry:
In the biotechnology industry, 1-methyltetrahydro-2(1H)-pyrimidinone (SALTDATA: FREE) may be utilized as a tool compound for studying the mechanisms underlying cell differentiation and the development of cancer. This could lead to a better understanding of the molecular pathways involved in these processes and the identification of new targets for therapeutic intervention.
Furthermore, the compound's potential applications in drug delivery systems and the development of novel drug formulations could also be explored, with the aim of improving the bioavailability, efficacy, and safety of existing and new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 10166-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,6 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10166-54:
(7*1)+(6*0)+(5*1)+(4*6)+(3*6)+(2*5)+(1*4)=68
68 % 10 = 8
So 10166-54-8 is a valid CAS Registry Number.
10166-54-8Relevant articles and documents
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Fox,van Praag
, p. 486,488 (1960)
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Catalytic oxidative carbonylation of primary and secondary α,ω-diamines to cyclic ureas
McCusker, Jennifer E.,Grasso, Cara A.,Main, Andrea D.,McEiwee-White, Lisa
, p. 961 - 964 (1999)
(matrix presented) Primary and secondary diamines can be catalytically carbonylated to cyclic ureas using W(CO)6 as the catalyst, I2 as the oxidant, and CO as the carbonyl source. Preparation of five-, six-, and seven-membered cyclic ureas from the diamines RNHCH2(CH2)nCH2NHR (n = 0-2; R = H, Me) and RNHCH2CH2NHR (R = Et, i-Pr, Bz) was achieved in moderate to good yields.
PROCESS FOR THE PRODUCTION OF CYCLIC GUANIDINE DERIVATES
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Page/Page column 10-11, (2021/04/30)
The present invention relates to a process for the production of cyclic guanidine derivates of formula I or mixtures of them (formula I) by reacting a triamine in the present of a C1-source and a solid material in the gas or liquid phase under inert atmosphere.
3-(Triflyloxy)benzynes Enable the Regiocontrolled Cycloaddition of Cyclic Ureas to Synthesize 1,4-Benzodiazepine Derivatives
Kaneko, Hideki,Ikawa, Takashi,Yamamoto, Yuta,Arulmozhiraja, Sundaram,Tokiwa, Hiroaki,Akai, Shuji
supporting information, p. 943 - 948 (2018/02/26)
A versatile synthesis of 1,4-benzodiazepine derivatives through the reaction of various 3-(trifluoromethanesulfonyloxy)benzynes with N -(p -toluenesulfonyl)imidazolidin-2-ones is reported. This reaction system provides a 1,4-benzodiazepine bearing a trifluoromethanesulfonyloxy group as a single regioisomer among the four possible regioisomers.
