1018471-52-7

Basic information

• Product Name: N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide
• CAS NO: 1018471-52-7
• Molecular Weight: 383.399
• Mol File: 1018471-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide(1018471-52-7)
• EPA Substance Registry System: N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide(1018471-52-7)

Safety Data

• Hazardous Substances Data: 1018471-52-7(Hazardous Substances Data)

Upstream product

• 1018471-46-9 N-(4-oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)methanesulfonamide 
• 2265-93-2 2,4-difluoro-1-iodobenzene 

Relevant articles and documents

Copper-catalyzed coupling reaction of 2-thioxo-4-quinazolinone and thieno[3,2-d]pyrimidin-4-one methane sulphonamide with aryl iodides: Preparation of potential COX-2 selective inhibitors

Thio-aryl methane sulfonamide derivatives of 4-quinazolinone and thieno[2,3-d]pyrimidin-4-one were synthesized using powdery copper/copper(I) iodide as catalyst; their structural elucidation is also reported. These derivatives were planned as sulfur bioisosteres of selective COX-2 inhibitor drugs. Copyright Taylor & Francis Group, LLC.