1019196-87-2

Basic information

• Product Name: 4-hydroxy-3-(4-methoxyphenyl)-5-methylfuran-2(5H)-one
• Synonyms: 4-hydroxy-3-(4-methoxyphenyl)-5-methylfuran-2(5H)-one
• CAS NO: 1019196-87-2
• Molecular Weight: 220.225
• Mol File: 1019196-87-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-3-(4-methoxyphenyl)-5-methylfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-3-(4-methoxyphenyl)-5-methylfuran-2(5H)-one(1019196-87-2)
• EPA Substance Registry System: 4-hydroxy-3-(4-methoxyphenyl)-5-methylfuran-2(5H)-one(1019196-87-2)

Safety Data

• Hazardous Substances Data: 1019196-87-2(Hazardous Substances Data)

Upstream product

• 27871-49-4 (S)-Methyl lactate 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 1589532-78-4 C₁₄H₁₈O₅ 
• 104-01-8 4-Methoxyphenylacetic acid 

Downstream Products

• 1589533-25-4 3-(4-methoxyphenyl)-5-(hydroxymethyl)-4-methoxyfuran-2(5H)-one 
• 1589532-57-9 3-(4-methoxyphenyl)-7a-methyl-7,7a-dihydrofuran[3,2-d][1,2]oxathin-5,5-dioxide-2(4H)-one 
• 1589533-36-7 C₁₅H₁₈O₇S 
• 1403350-14-0 C₁₃H₁₄O₄ 

Relevant articles and documents

Synthesis and anti-BVDV activity of novel δ-sultones in vitro: Implications for HCV therapies

In this study we report the synthesis and activity against bovine viral diarrhea virus (BVDV) of a novel series of bicycle δ-sultones containing γ-lactones. BVDV is responsible for major losses in cattle. Some of the synthesized δ-sultones showed pronounced anti-BVDV activity with EC 50 values of 0.12-1.0 μM and no significant cytotoxicity. Among them, the ortho bromosubstituted derivative 4f (EC50 = 0.12 μM) showed better antiviral activity than other derivatives and was 10 fold more that of than positive control ribavirin (EC50 = 1.3 μM). BVDV is also considered to be a valuable surrogate for the hepatitis C virus (HCV) in antiviral drug studies. The above results provided a novel candidate for the development of anti-HCV agents.