1020172-95-5

Basic information

• Product Name: (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol
• Synonyms: (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol
• CAS NO: 1020172-95-5
• Molecular Weight: 234.23
• Mol File: 1020172-95-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol(1020172-95-5)
• EPA Substance Registry System: (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol(1020172-95-5)

Safety Data

• Hazardous Substances Data: 1020172-95-5(Hazardous Substances Data)

Usage

Description

(5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol is a chemical compound with the molecular formula C13H12N2O2F. It is a pyridine derivative containing a fluorophenoxy group and an amino group. (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol has potential applications in medicinal chemistry and drug development, as it may exhibit biological activity that could be useful in the treatment of certain diseases. Its structure and properties make it a subject of interest for researchers and scientists in the field of pharmaceuticals. Further studies are likely being conducted to explore its potential uses and effects.

Uses

Used in Pharmaceutical Industry:
(5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol is used as a chemical compound for its potential medicinal applications. Its unique structure, which includes a fluorophenoxy group and an amino group, suggests that it may have biological activity that could be harnessed for the treatment of various diseases. Researchers and scientists are likely exploring its potential uses and effects in drug development.
Used in Medicinal Chemistry Research:
(5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol is used as a subject of interest for researchers and scientists in the field of medicinal chemistry. Its structure and properties make it a promising candidate for further study and potential development into new drugs or therapies. (5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methanol's fluorophenoxy and amino groups may contribute to its biological activity, which could be beneficial in the treatment of certain diseases.

Upstream product

• 84478-75-1 2-chloro-4-fluoro-5-nitrophenol 
• 84478-89-7 2-chloro-4-fluoro-5-nitro-methoxycarbonyloxybenzene 
• 84478-88-6 2-chloro-4-fluoro-methoxycarbonyloxybenzene 
• 1996-41-4 2-chloro-4-fluorophenol 
• 97483-77-7 2-Cyano-5-bromopyridine 
• 1020173-02-7 5-(3-amino-4-fluorophenoxy)picolinonitrile 
• 62257-16-3 5-hydroxy-2-fluoroaniline 
• 1020172-94-4 5-(3-amino-4-fluorophenoxy)picolinic acid 

Downstream Products

• 1020172-96-6 2-fluoro-5-(6-methylpyridin-3-yloxy)benzenamine 
• 1025456-64-7 O-(5-(3-amino-4-fluorophenoxy)pyridin-2-yl)methyl S-methyl carbonodithioate 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES

Compounds of the present invention find utility in the treatment of hyperproliferative diseases, mammalian cancers and especially human cancers including but not limited to malignant, melanomas, glioblastomas, ovarian cancer, pancreatic cancer, prostate cancer, lung cancers, breast cancers, kidney cancers, cervical carcinomas, metastasis of primary tumor sites secondary sites, myeloproliferative diseases, chronic myelogenous leukemia, acute lymphocytic leukemia, papillary thyroid carcinoma, non small cell lung cancer, mesothelioma, hypereosinophilic syndrome, gastrointestinal stromal tumors, colonic cancers, thyroid cancer, ocular diseases characterized by hyperproliferation leading to blindness including various retinopathies, i.e. diabetic retinopathy and age-related macular degeneration, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, human inflammation, rheumatoid spondylitis, ostero-arthritis, asthma, gouty arthritis, sepsis, septic shock, endotoxic shock, Gram-negative sepsis, toxic shock syndrome, adult respiratory distress syndrome, stroke, reperfusion injury, neural trauma, neural ischemia, psoriasis, restenosis, chronic obstructive pulmonary disease, bone resorptive diseases, graft-versus-host reaction, Crohn's disease, ulcerative colitis, inflammatory bowel disease, pyresis, and combinations thereof, a disease caused by c-ABL kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, c-KIT kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, VEGFR kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, PDGFR kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, FLT-3 kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, TIE-2 kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, TRK kinases, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, c-MET kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof, or a disease caused by a HER kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof.