1025358-49-9

Basic information

• Product Name: 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)adenosine
• Synonyms: 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)adenosine
• CAS NO: 1025358-49-9
• Molecular Weight: 626.788
• Mol File: 1025358-49-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)adenosine(1025358-49-9)
• EPA Substance Registry System: 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]-N⁶-(N-phenylcarbamoyl)adenosine(1025358-49-9)

Safety Data

• Hazardous Substances Data: 1025358-49-9(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 1025358-26-2 2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]-5'-[(N-methylcarbamoyl)amino]adenosine 
• 152965-11-2 2'-O-(tert-butyldimethylsilyl)-3'-[(ethoxycarbonyl)methyl]-3'-deoxyadenosine 
• 1025358-17-1 5'-azido-2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]adenosine 
• 1025358-14-8 2'-O-(tert-butyldimethylsilyl)-3'-deoxy-3'-[(ethoxycarbonyl)methyl]-5'-O-(p-toluenesulfonyl)adenosine 
• 5819-21-6 4-nitrophenyl N-methylcarbamate 

Downstream Products

• 1025358-64-8 3'-(carboxymethyl)-3',5'-dideoxy-5'-[(N-methylcarbamoyl)amino]-N₆-(N-phenylcarbamoyl)adenosine-2',3'-lactone 

Relevant articles and documents

Preliminary SAR analysis of novel antiproliferative N6,5′-bis-ureidoadenosine derivatives

A preliminary library of novel N6,5′-bis-ureidoadenosine analogs and related derivatives was prepared and tested for activity against the NCI 60 panel of human cancers. A 2′-O-TBS group was found to be necessary, but not sufficient, for optimal

Design, synthesis, and antiviral evaluation of some 3′-carboxymethyl- 3′-deoxyadenosine derivatives

3′-Carboxymethyl-3′-deoxyadenosine derivatives were prepared from 2′-O-TBDMS-3′-[(ethoxycarbonyl)methyl]-3′-deoxyadenosine (1) via simple and efficient procedures. Conversion of 1 to its 5′-azido-5′-deoxy derivative 5 was accomplished via a novel one-pot