10266-13-4

Basic information

• Product Name: Quinoline, 3-methyl-2,4-diphenyl-
• CAS NO: 10266-13-4
• Molecular Formula: C22H17N
• Molecular Weight: 295.384
• Mol File: 10266-13-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Quinoline, 3-methyl-2,4-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 3-methyl-2,4-diphenyl-(10266-13-4)
• EPA Substance Registry System: Quinoline, 3-methyl-2,4-diphenyl-(10266-13-4)

Safety Data

• Hazardous Substances Data: 10266-13-4(Hazardous Substances Data)

Upstream product

• 72374-63-1 N-(4-Methylphenyl)-1-phenylpropanimine 
• 71115-30-5 2-Methyl-3-(4-methylphenylamino)-1,3-diphenyl-2-propenimine 
• 14752-72-8 1,N-Diphenylpropanimine 
• 138356-04-4 3-imino-1,3,N-triphenyl-2-methylprop-1-enylamine 
• 93-54-9 1-Phenyl-1-propanol 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 673-32-5 1-Phenylprop-1-yne 
• 538-51-2 benzylidene phenylamine 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 13209-38-6 (2-aminophenyl)(phenyl)methanol 
• 93-55-0 1-phenyl-propan-1-one 
• 1561153-03-4 3-methyl-2-(methylthio)-4-phenylquinoline 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 88795-69-1 1-Ethyl-3-methyl-4-phenyl-1H-quinolin-2-one 

Relevant articles and documents

Catalyst free indirect Friedlaender synthesis of substituted quinolines from alcohols in PEG-400

The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG-400 as reaction medium in the presence of a base, without any transition-metal catalyst.

One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene

Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates.

Highly Diastereo- And Enantioselective Ir-Catalyzed Hydrogenation of 2,3-Disubstituted Quinolines with Structurally Fine-Tuned Phosphine-Phosphoramidite Ligands

A highly diastereo- and enantioselective Ir-catalyzed hydrogenation of unfunctionalized 2,3-disubstituted quinolines, especially 3-alkyl-2-arylquinolines, has been realized. The success of this hydrogenation is ascribed to the use of a structurally fine-tuned chiral phosphine-phosphoramidite ligand with a (Sa)-3,3′-dimethyl H8-naphthyl moiety and (Rc)-1-phenylethylamine backbone. The hydrogenation displayed broad functional group tolerance, thus furnishing a wide range of optically active 2,3-disubstituted tetrahydroquinolines in up to 96% ee and with perfect cis-diastereoselectivity.

Palladium-Catalyzed [5+1] Annulation of 2-(1-Arylvinyl) Anilines and α-Diazocarbonyl Compounds toward Multi-functionalized Quinolines

A palladium-catalyzed [5+1] annulation of 2-(1-arylvinyl) anilines and α-diazocarbonyl compounds has been developed, affording a series of multi-functionalized quinolines in moderate to good yields. This procedure proceeded with the sequential insertion o