1026732-79-5

Basic information

• Product Name: 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester
• Synonyms: 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester
• CAS NO: 1026732-79-5
• Molecular Weight: 438.629
• Mol File: 1026732-79-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester(1026732-79-5)
• EPA Substance Registry System: 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester(1026732-79-5)

Safety Data

• Hazardous Substances Data: 1026732-79-5(Hazardous Substances Data)

Upstream product

• 221629-44-3 methyl 7-(2-hydroxy-5-(2-(2-oxiranyl)ethyl)-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate 
• 221629-43-2 7-[(1R,2R,3R,5S)-2-But-3-enyl-3-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-cyclopentyl]-heptanoic acid methyl ester 
• 221629-33-0 methyl 7-(5-but-3-enyl-2-hydroxy-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate 
• 41138-61-8 (4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone 
• 41138-69-6 7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester 

Relevant articles and documents

Design and synthesis of 13,14-dihydro prostaglandin F(1α) analogues as potent and selective ligands for the human FP receptor

The in vitro evaluation of a new class of potential bone anabolic agents for the treatment of osteoporosis is described. These compounds are potent and selective ligands for the human prostaglandin F receptor (hFP receptor). The compounds lack the olefin unsaturation required for potency in the natural ligand PGF(2α) yet retain binding affinity for the hFP receptor in the nanomolar to micromolar range. Removal of the alkenes also results in a better selectivity ratio for the hFP receptor over the other prostaglandin receptors tested. A rationale for the selectivity differences of various analogues, based on ligand docking experiments to a putative hFP receptor model, is also described.