10270-11-8 Usage
Chemical class
Pyrrole-2,5-dione derivatives
Physical state
Yellow solid
Usage
Catalyst in chemical reactions (specifically esterification and amidation)
Application
Synthesis of pharmaceuticals and agrochemicals
Chemical property
Acts as a nucleophile
Bonding
Forms strong covalent bonds with other molecules
Importance
Valuable tool in organic synthesis
Safety precautions
Harmful if ingested or inhaled, causes skin and eye irritation, should be handled with caution
Check Digit Verification of cas no
The CAS Registry Mumber 10270-11-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,7 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10270-11:
(7*1)+(6*0)+(5*2)+(4*7)+(3*0)+(2*1)+(1*1)=48
48 % 10 = 8
So 10270-11-8 is a valid CAS Registry Number.
10270-11-8Relevant articles and documents
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Rubinstein et al.
, p. 3372 (1971)
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Access to indoles via Diels-Alder reactions of 2-vinylpyrroles with maleimides
Noland, Wayland E.,Lanzatella, Nicholas P.,Venkatraman, Lakshmanan,Anderson, Nicholas F.,Gullickson, Glen C.
experimental part, p. 1154 - 1176 (2010/03/04)
(Chemical Equation Presented) Variously substituted 2-vinylpyrroles underwent an endo-addition [4+2] cycloaddition reaction with maleimides followed by a spontaneous highly diastereoselective (93-98% de) isomerization to give tetrahydroindoles in moderate to excellent yield. Treatment with activated MnO2 in refluxing toluene provided the corresponding indoles in moderate to good yield. This highly convergent methodology for formation of indoles is versatile and the starting materials are conveniently prepared.
