103548-00-1Relevant articles and documents
Butyrolactone synthesis via polar radical crossover cycloaddition reactions: Diastereoselective syntheses of methylenolactocin and protolichesterinic acid
Zeller, Mary A.,Riener, Michelle,Nicewicz, David A.
, p. 4810 - 4813 (2014)
A direct catalytic synthesis of γ-butyrolactones from simple alkene and unsaturated acid starting materials is reported. The catalytic system consists of the Fukuzumi acridinium photooxidant and substoichiometric quantities of a redox-active cocatalyst. Oxidizable alkenes such as styrenes and trisubstituted aliphatic alkenes are cyclized with unsaturated acids via polar radical crossover cycloaddition (PRCC) reactions. This method has been applied to the diastereoselective total synthesis of methylenolactocin and protolichesterinic acid.
An efficient synthesis of α-methylene-β-butyrolactones from Baylis-Hillman adducts via an In-mediated Barbier reaction and stereoselective lactonization under MeSO2Cl/Et3N conditions
Park, Bo Ram,Kim, Ko Hoon,Kim, Jae Nyoung
, p. 6568 - 6571 (2011/03/17)
An efficient synthesis of trans-α-methylene-β-butyrolactones is disclosed from syn-homoallylic alcohols via the intramolecular mesylate displacement reaction promoted by nearby ester group under the influence of MsCl/Et3N. syn-Homoallylic alcoh
SYNTHESIS OF α-METHYLENE-γ-LACTONES VIA Cr AND Sn COMPLEXES OF β-CARBETHOXY AND β-NITRILE ALLYL BROMIDES
Drewes, S. E.,Hoole, R. F. A.
, p. 1067 - 1074 (2007/10/02)
The synthesis of some α-methylene-γ-lactones employing allylic Cr and Sn complexes is described.
