104149-51-1

Basic information

• Product Name: Pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(4H)-one (9CI)
• Synonyms: Pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(4H)-one (9CI);PYRIDO[2,3-E]PYRROLO[1,2-A]PYRAZIN-6(5H)-ONE
• CAS NO: 104149-51-1
• Molecular Formula: C10H7N3O
• Molecular Weight: 185.18208
• Product Categories: PIPERIDINE
• Mol File: 104149-51-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(4H)-one (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(4H)-one (9CI)(104149-51-1)
• EPA Substance Registry System: Pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(4H)-one (9CI)(104149-51-1)

Safety Data

• Hazardous Substances Data: 104149-51-1(Hazardous Substances Data)

Upstream product

• 13534-99-1 2-Amino-3-bromopyridine 
• 147-85-3 L-proline 
• 104149-45-3 acide (chloro-2-pyridyl-3)-1-pyrrolyl Carboxylique-2 
• 104149-38-4 (pyrrolyl-1)-3 picolinate de methyle 
• 97580-57-9 (chloro-2-pyridyl-3)-1-pyrrolyl-2 carboxaldehyde 
• 104149-39-5 hydroxy-2 (pyrolyl-1)-3 pyridine 
• 73955-73-4 hydrazide de l'acide(pyrrolyl-1)-3 picolinique-2 
• 70291-26-8 2-chloro-3-(1H-pyrrol-1-yl)pyridine 
• 33630-99-8 2-hydroxy-3-aminopyridine 
• 6298-19-7 2-chloro-3-aminopyridine 
• 109701-77-1 2-fluoro-3-(1H-pyrrol-1-yl)pyridine 
• 1597-33-7 2-fluoro-3-pyridinylamine 
• 251649-50-0 (3-nitropyridin-2-yl)carbamic acid benzyl ester 
• 108655-55-6 (3-aminopyridin-2-yl)carbamic acid benzyl ester 

Relevant articles and documents

Synthesis of Kappa Opioid Antagonists Based on Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence

The quinoxaline and quinoxalinone family of nitrogen heterocycles is present in molecules of therapeutic relevance for diverse applications ranging from infectious diseases to neuroscience targets. Here, we describe a general synthetic sequence to afford pyrrolo[1,2-α]quinoxalinones from commercially available starting materials and their use in preparing potential kappa opioid receptor antagonists. The biological data obtained from the latter set of compounds is briefly presented and discussed.

REINVESTIGATION OF A CYCLIZATION REACTION OF 2-HYDRAZINO-3-(1H-PYRROL-1-YL)PYRIDINE

The reaction of 2-hydrazino-3-(1H-pyrrol-1-yl)pyridine (3) with acetylacetone affords 2-(3,5-dimethyl-1H-pyrazol-1-yl)-3-(1H-pyrrol-1-yl)pyridine (7) rather than 3,5-dimethyl-10-(1H-pyrrol-1-yl)pyridotriazepine (5), as previously reported.