1042737-42-7Relevant articles and documents
Pd-Catalyzed Intramolecular Cyclization via Direct C-H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles
Wang, Ting-Ting,Zhao, Lang,Zhang, Yan-Jing,Liao, Wei-Wei
, p. 5002 - 5005 (2016)
The first example of Pd-catalyzed intramolecular C-H addition of indoles bearing cyanohydrin components at the C(3), C(2), and N(1) positions to nitriles is described. A wide range of functionalized partially saturated carbazoles, tetrahydropyrido[1,2-a]indole, and carbazoles can be prepared in good to excellent yields under the optimal conditions. In addition, fused polycyclic indoles with seven- or eight-membered rings can also be formed smoothly.
Cu-catalyzed β-functionalization of saturated ketones with indoles: A one-step synthesis of C3-substituted indoles
Yang, Zhao,Liu, Chengkou,Zeng, Yu,Zhang, Jingming,Wang, Zhixiang,Fang, Zheng,Guo, Kai
, p. 89181 - 89184 (2016/10/03)
An effective one-pot synthesis of β-indolylketones from saturated ketones and indoles was developed. It is noteworthy that this methodology has a good functional group tolerance (alkyl, nitro, halogen, hydroxyl, methoxyl, carboxyl and ester) and is of great significance to the preparation of many indole heterocycles.