104613-64-1 Usage
General Description
2-Amino-4-chloro-5-methylbenzenesulfonyl chloride, also known as 4-chloro-2-methylbenzenesulfonyl chloride, is a chemical compound with the molecular formula C7H7Cl2NO2S. It is a sulfonyl chloride compound, which is commonly used in organic synthesis as a reagent for introducing the sulfonyl chloride functional group. It is a highly reactive intermediate that can be used in the production of various pharmaceuticals and agrochemicals. The compound is also used in the manufacturing of dyes, pigments, and other fine chemicals. Due to its reactivity and potential to cause irritation to the skin and eyes, precautions should be taken when handling this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 104613-64-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,6,1 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 104613-64:
(8*1)+(7*0)+(6*4)+(5*6)+(4*1)+(3*3)+(2*6)+(1*4)=91
91 % 10 = 1
So 104613-64-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7Cl2NO2S/c1-4-2-7(13(9,11)12)6(10)3-5(4)8/h2-3H,10H2,1H3
104613-64-1Relevant articles and documents
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site
Gopalsamy, Ariamala,Chopra, Rajiv,Lim, Kitae,Ciszewski, Gregory,Shi, Mengxiao,Curran, Kevin J.,Sukits, Steven F.,Svenson, Kristine,Bard, Joel,Ellingboe, John W.,Agarwal, Atul,Krishnamurthy, Girija,Howe, Anita Y. M.,Orlowski, Mark,Feld, Boris,O'Connell, John,Mansour, Tarek S.
, p. 3052 - 3055 (2007/10/03)
Through high throughput screening, substituted proline sulfonamide 6 was identified as HCV NS5b RNA-dependent RNA polymerase inhibitor. Optimization of various regions of the lead molecule resulted in compounds that displayed good potency and selectivity.
