104863-65-2

Basic information

• Product Name: N-METHOXY-N-METHYL-PROPIONAMIDE
• Synonyms: N-METHOXY-N-METHYL-PROPIONAMIDE
• CAS NO: 104863-65-2
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.14634
• Mol File: 104863-65-2.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 119°C at 760 mmHg
• Flash Point: 25.8°C
• Appearance: /
• Density: 0.961g/cm³
• Vapor Pressure: 16.3mmHg at 25°C
• Refractive Index: 1.4270 to 1.4310
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-METHOXY-N-METHYL-PROPIONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHOXY-N-METHYL-PROPIONAMIDE(104863-65-2)
• EPA Substance Registry System: N-METHOXY-N-METHYL-PROPIONAMIDE(104863-65-2)

Safety Data

• RIDADR: UN 1993 3/PG III
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 104863-65-2(Hazardous Substances Data)

Usage

General Description

N-Methoxy-N-methyl-propionamide is a chemical compound with the molecular formula C6H13NO2. It is a clear, colorless liquid with a faint odor and is often used as a solvent in various industrial applications. N-METHOXY-N-METHYL-PROPIONAMIDE is known for its high boiling point and low volatility, making it an effective solvent for a wide range of substances. It is also used as an intermediate in the production of pharmaceuticals and agrochemicals. Additionally, N-methoxy-N-methyl-propionamide has been found to have potential applications in the field of organic synthesis and as a stabilizer for certain chemical reactions. Overall, this chemical compound is valued for its solvent properties and its versatility in various industrial processes.

InChI:InChI=1/C5H11NO2/c1-4-5(7)6(2)8-3/h4H2,1-3H3

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 802294-64-0 propionic acid 
• 123-62-6 propionic acid anhydride 
• 79-03-8 propionyl chloride 
• 1117-97-1 N,0-dimethylhydroxylamine 

Downstream Products

• 121-97-1 4-Methoxypropiophenone 
• 711-33-1 4-trifluoromethyl propiophenone 
• 26672-58-2 1-(4-dimethylaminophenyl)propan-1-one 
• 456-03-1 1-(4-fluorophenyl)propan-1-one 
• 1207459-38-8 C₂₀H₃₂N₂O₅S 
• 1233735-51-7 1-(1-o-tolyl-1H-imidazol-2-yl)propan-1-one 
• 59303-13-8 1-(5-methylthiophen-2-yl)propan-1-one 
• 1233735-48-2 1-(1-phenyl-1H-imidazol-2-yl)propan-1-one 
• 23757-10-0 1-(5-iodothiophen-2-yl)propan-1-one 
• 1205539-04-3 (R(S),2S,3R)-(-)-N-Methoxy-N,2-dimethyl-3-(2,4,6-triisopropylphenylsulfonamido)-5-benzyloxypentanamide 
• 1205539-03-2 C₃₀H₄₆N₂O₄S 
• 1138339-21-5 (SS,2R,3S)-(+)-(+)-N-(p-toluenesulfinyl)-3-amino-N-methoxy-N,2-dimethyl-5-(2-methyl-1,3-dioxolan-2-yl)pentanamide 
• 19307-74-5 1-phenyl-pent-1-yn-3-one 
• 1015070-29-7 4-Fluoro-3-propanoyl-benzenecarbonitrile 

Relevant articles and documents

Enantioselective Mannich Reaction Employing 1,3,5-Triaryl-1,3,5-triazinanes Catalyzed by Chiral-at-Metal Rhodium Complexes

Chiral-at-metal RhIII complexes catalyze the efficient enantioselective Mannich reaction of 2-acyl imidazoles with 1,3,5-triazinanes, affording the corresponding adducts in 81–99 % yield with up to >99 % enantioselectivity. This protocol performs with 0.1 mol-% of RhIII complex on gram scale without any loss in enantioselectivity.

Iron-Catalyzed Michael Addition of Ketones to Polar Olefins

The base metal complex tetrabutylammonium nitrosyltricarbonylferrate {Bu4N[Fe(CO)3(NO)] (TBA[Fe])} – catalyzes the conjugate addition of ketones to polar olefins. The reaction is applicable to a wide range of substrates leading to interesting building blocks for organic synthesis. Clear indications for an acid-base type rather than a C?H activation pathway exist. (Figure presented.).

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The present invention discloses compounds according to Formula I: wherein R1, R2, R3, R4, L, and X are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical