104874-86-4 Usage
Description
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)is a complex organic compound with a unique molecular structure. It is characterized by the presence of a piperazine ring, a quinazolinyl moiety, and a benzodioxinyl group. Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)exhibits a range of biological activities and has potential applications in various fields due to its structural diversity and functional groups.
Uses
Used in Pharmaceutical Industry:
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)is used as a pharmaceutical agent for the development of novel drugs targeting various diseases. Its unique structure and functional groups allow for the modulation of specific biological pathways, making it a promising candidate for the treatment of conditions such as cancer, inflammation, and neurological disorders.
Used in Chemical Research:
In the field of chemical research, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)serves as a valuable compound for studying the synthesis and modification of complex organic molecules. Its unique structure provides opportunities for the development of new synthetic methods and the exploration of novel chemical reactions.
Used in Drug Delivery Systems:
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)can be employed in the development of advanced drug delivery systems. Its structural features and functional groups can be utilized to improve the solubility, stability, and bioavailability of therapeutic agents, leading to enhanced efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)may find applications as a component in the development of novel pesticides or herbicides. Its unique structure and functional groups can be exploited to target specific pests or weeds, providing more effective and environmentally friendly solutions for agricultural challenges.
Used in Material Science:
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, (S)can also be explored for its potential applications in material science. Its structural features and functional groups may contribute to the development of new materials with unique properties, such as improved mechanical strength, thermal stability, or electrical conductivity.
Check Digit Verification of cas no
The CAS Registry Mumber 104874-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,8,7 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 104874-86:
(8*1)+(7*0)+(6*4)+(5*8)+(4*7)+(3*4)+(2*8)+(1*6)=134
134 % 10 = 4
So 104874-86-4 is a valid CAS Registry Number.
104874-86-4Relevant articles and documents
A reliable multigram synthesis of (±) doxazosin
Kumaraswamy,Das,Jena, Nivedita
, p. 603 - 608 (2003)
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Method for synthesizing doxazosin
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Paragraph 0063; 0077; 0078; 0079, (2017/01/12)
The invention discloses a method for synthesizing doxazosin and belongs to the technical field of chemical synthesis. According to the method, the doxazosin is synthesized by adopting a synthesis route, represented by formulae shown in the description, different from the conventional technologies, and thus a novel synthesis route is provided for preparing the doxazosin; and the method has the advantages of moderate conditions, simple and convenient steps and high yield, and the doxazosin can be obtained simply and efficiently.
Chemoenzymatic synthesis of piperoxan, prosympal, dibozane, and doxazosin
Rouf, Abdul,Gupta, Pankaj,Aga, Mushtaq A.,Kumar, Brijesh,Chaubey, Asha,Parshad, Rajinder,Taneja, Subhash C.
, p. 1615 - 1623 (2013/02/22)
The synthesis of both enantiomers of 1,4-benzodioxan-2-carboxylic acid 1, a key synthetic intermediate for the therapeutic agents piperoxan, prosympal, dibozane, and doxazosin was achieved with good yields and high enantioselectivities via the Arthrobacter sp. lipase catalyzed kinetic resolution of ester (±)-17a. The influence of the co-solvents and the immobilization of the lipase upon kinetic resolution demonstrated that immobilized whole cells, in the presence of n-butanol as a co-solvent, resulted in the optimal resolution of the substrate (ee ～99%, E = 535) at 258 mmol (50 g/L) substrate concentration.
THERAPY FOR COMPLICATIONS OF DIABETES
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, (2009/07/02)
A method for enhancing glycemic control and/or insulin sensitivity in a human subject having diabetic nephropathy and/or metabolic syndrome comprises administering to the subject a selective endothelin A (ETA) receptor antagonist in a glycemic control and/or insulin sensitivity enhancing effective amount. A method for treating a complex of comorbidities in an elderly diabetic human subject comprises administering to the subject a selective ETA receptor antagonist in combination or as adjunctive therapy with at least one additional agent that is (i) other than a selective ETA receptor antagonist and (ii) effective in treatment of diabetes and/or at least one of said comorbidities other than hypertension. A therapeutic combination useful in such a method comprises a selective ETA receptor antagonist and at least one antidiabetic, anti-obesity or antidyslipidemic agent other than a selective ETA receptor antagonist.
