1051405-47-0

Basic information

• Product Name: C₄₆H₆₃NO₁₅
• Synonyms: C₄₆H₆₃NO₁₅
• CAS NO: 1051405-47-0
• Molecular Weight: 870.004
• Mol File: 1051405-47-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₄₆H₆₃NO₁₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₆H₆₃NO₁₅(1051405-47-0)
• EPA Substance Registry System: C₄₆H₆₃NO₁₅(1051405-47-0)

Safety Data

• Hazardous Substances Data: 1051405-47-0(Hazardous Substances Data)

Upstream product

• 1051405-83-4 C₄₃H₆₁NO₁₅ 
• 849213-19-0 C₆₅H₇₇NO₁₉ 
• 943239-54-1 C₄₃H₆₈O₁₁Si₂ 
• 943239-53-0 C₄₁H₆₆O₁₀Si₂ 
• 651293-82-2 7,13-bis(triethylsilyl)-10-dehydro-10-deacetylbaccatin III 
• 92950-45-3 10-dehydro 10-deacetyl 7-epibaccatin V 
• 32981-86-5 10-deacetylbaccatin III 

Relevant articles and documents

TAXANE ANALOGUES, THEIR USE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION

The present invention relates to novel taxane analogues, processes of making the novel taxane analogues, compositions containing the novel taxane analogues, and their use in treating cancer and neurodegenerative disorders. In some embodiments, the taxane analogues are represented by the generic structure of formula (I) : wherein R1, R2,R3 and A are defined herein; and esters especially pro-drugs thereof wherein one or more of the hydroxy! groups is esterified to form an in-vivo hydrolysable ester group; or pharmaceutically acceptable salts thereof.

TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER

Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a s