1057253-65-2

Basic information

• Product Name: (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate
• Synonyms: (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate
• CAS NO: 1057253-65-2
• Molecular Weight: 352.436
• Mol File: 1057253-65-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate(1057253-65-2)
• EPA Substance Registry System: (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate(1057253-65-2)

Safety Data

• Hazardous Substances Data: 1057253-65-2(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 107484-93-5 C₁₀H₁₁BrMgO₂ 
• 6429-44-3 (S)-(-)-N-(benzyloxycarbonyl)alaninol 
• 39172-32-2 2-(3-bromophenyl)-2-methyl-[1,3]dioxolane 
• 946088-69-3 C₉H₉BrMg 
• 946088-68-2 benzyl 2-methylaziridine-1-carboxylate 
• 881206-91-3 (S)-benzyl 1-(3-acetylphenyl)propan-2-ylcarbamate 
• 872059-44-4 [2-(3-bromo-phenyl)-1S-methyl-ethyl]-carbamic acid benzyl ester 
• 849831-52-3 3-(3-bromophenyl)-2-methylpropionic acid 
• 1057253-68-5 (S)-benzyl 1-(3-(2-hydroxypropan-2-yl)phenyl)propan-2-ylcarbamate 
• 501-53-1 benzyl chloroformate 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 30951-66-7 2-(3-bromophenyl)-2-propanol 
• 25108-58-1 1-bromo-3-isopropenylbenzene 

Downstream Products

• 894791-74-3 (S)-1-(3-(2-Aminopropan-2-yl)phenyl)propan-2-amine 

Relevant articles and documents

Comparative approaches toward diamines containing spatially separated homobenzylic and benzylic nitrogen stereocenters

Several synthetic strategies to diamines 1-3 are described. The optimum approach via opening of aziridine afforded 1-3 in 29-60% yield over 3-5 steps. A study on formation of the benzylic stereocenter using Toste's rhenium-catalyzed asymmetric reduction of phosphinyl ketimines was also evaluated and afforded 15 in 92% de.