106281-22-5

Basic information

• Product Name: 1H-Pyrrolizine-3-carboxylicacid,hexahydro-5-oxo-,cis-(9CI)
• Synonyms: 1H-Pyrrolizine-3-carboxylicacid,hexahydro-5-oxo-,cis-(9CI)
• CAS NO: 106281-22-5
• Molecular Formula: C8H11NO3
• Molecular Weight: 0
• Product Categories: PYRROLE
• Mol File: 106281-22-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolizine-3-carboxylicacid,hexahydro-5-oxo-,cis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolizine-3-carboxylicacid,hexahydro-5-oxo-,cis-(9CI)(106281-22-5)
• EPA Substance Registry System: 1H-Pyrrolizine-3-carboxylicacid,hexahydro-5-oxo-,cis-(9CI)(106281-22-5)

Safety Data

• Hazardous Substances Data: 106281-22-5(Hazardous Substances Data)

Upstream product

• 1197-13-3 methyl 5-formyl-1H-pyrrole-2-carboxylate 
• 106281-19-0 methyl 5-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-1H-pyrrole-2-carboxylate 
• 106281-18-9 methyl 5-<(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl>-1H-pyrrole-2-carboxylate 
• 106281-20-3 methyl 5-(β-methoxycarbonylethyl)-1H-pyrrole-2-carboxylate 
• 106281-21-4 (2R,5S)-5-(2-Methoxycarbonyl-ethyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 112980-17-3 (3R,7aR)-5-Oxo-hexahydro-pyrrolizine-3-carboxylic acid methyl ester 
• 112980-17-3 (3R,7aS)-5-Oxo-hexahydro-pyrrolizine-3-carboxylic acid methyl ester 

Relevant articles and documents

Selective Synthesis of the Two Diastereomers of 5-Oxo-1H-pyrrolizine-3-carboxylic Acid

The rhodium catalysed reduction of a 2,5-disubstituted pyrrole 5 occurred selectively with the cis addition of hydrogen.The resulting cis-pyrrolidine was either cyclized without epimerization in refluxing toluene to the pyrrolizine 7 or with epimerization in refluxing acetic acid to the pyrrolizine 9.