106412-43-5

Basic information

• Product Name: 2-Ethoxy-piperidine-1-carboxylic acid benzyl ester
• Synonyms: 2-Ethoxy-piperidine-1-carboxylic acid benzyl ester
• CAS NO: 106412-43-5
• Molecular Weight: 263.337
• Mol File: 106412-43-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Ethoxy-piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethoxy-piperidine-1-carboxylic acid benzyl ester(106412-43-5)
• EPA Substance Registry System: 2-Ethoxy-piperidine-1-carboxylic acid benzyl ester(106412-43-5)

Safety Data

• Hazardous Substances Data: 106412-43-5(Hazardous Substances Data)

Upstream product

• 1468-47-9 5,5-diethoxy-valeronitrile 
• 21938-23-8 5-Aminopentanal Diethyl Acetal 
• 6139-83-9 4-chloro-1,1-diethoxybutane 
• 493009-88-4 benzyl 5,5-diethoxypentylcarbamate 
• 64-17-5 ethanol 
• 106412-35-5 N-benzyloxycarbonyl-2-piperidone 

Downstream Products

• 113-45-1 methyl (R*)-2-phenyl-2-((S*)-piperidin-2-yl)acetate 
• 113-45-1 dl-threo-methylphenidate 

Relevant articles and documents

Solid-phase synthesis of piperidines by N-acyliminium ion chemistry

An efficient solid-phase procedure for the synthesis of a number of 2-substituted piperidines is reported. Starting from solid-supported carbamate -tethered δ-amino acetals, 2- benzotriazolyl- substituted (Bt-substituted) piperidines were obtained by acid-induced ring-closure followed by trapping of the transient N-acyliminium ions with benzotriazole. These 2-Bt-substituted piperidines were then used as precursors for the successful introduction of several C-nucleophiles by N-acyliminium ion chemistry. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.