106833-44-7

Basic information

• Product Name: (E)-3-(4-methoxyphenyl)pent-2-enedioic acid
• Synonyms: (E)-3-(4-methoxyphenyl)pent-2-enedioic acid
• CAS NO: 106833-44-7
• Molecular Weight: 236.224
• Mol File: 106833-44-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-methoxyphenyl)pent-2-enedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-methoxyphenyl)pent-2-enedioic acid(106833-44-7)
• EPA Substance Registry System: (E)-3-(4-methoxyphenyl)pent-2-enedioic acid(106833-44-7)

Safety Data

• Hazardous Substances Data: 106833-44-7(Hazardous Substances Data)

Upstream product

• 857793-99-8 2-bromo-3-(4-methoxy-phenyl)-glutaric acid diethyl ester 
• 542-05-2 acetonedicarboxylic acid 
• 108-95-2 phenol 
• 857793-72-7 2-bromo-3-(4-hydroxy-phenyl)-glutaric acid diethyl ester 
• 33868-66-5 3-(4-hydroxy-phenyl)-glutaric acid diethyl ester 
• 33868-73-4 diethyl 3-(4-methoxyphenyl)pentanedioate 
• 70410-34-3 3-(4-hydroxyphenyl)pentanedioic acid 
• 33868-91-6 3-(4-methoxyphenyl)glutaric acid 
• 100-66-3 methoxybenzene 
• 50670-02-5 cis-sphagnum acid 
• 104-94-9 4-methoxy-aniline 
• 5164-76-1 dimethyl glutaconate 
• 123155-78-2 4-methoxybenzenediazonium 4-methylbenzenesulfonate 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 111585-92-3 1-benzyloxy-4-(4-methoxy-phenyl)-3H-pyridine-2,6-dione 
• 111412-00-1 1-benzyl-4-(4-methoxy-phenyl)-3H-pyridine-2,6-dione 
• 100373-18-0 1-hydroxy-6-methoxy-4-(4-methoxy-phenyl)-1H-pyridin-2-one 
• 114889-75-7 1-hydroxy-4-(4-methoxy-phenyl)-3H-pyridine-2,6-dione 
• 109694-32-8 1-benzyloxy-6-methoxy-4-(4-methoxy-phenyl)-1H-pyridin-2-one 
• 80986-02-3 4-(4-methoxyphenyl)-1-phenyl-2,6(1H,3H)-pyridinedione-3-carboxaldehyde 
• 67075-07-4 4-(4-methoxyphenyl)-1-phenyl-(1H,3H)-pyridine-2,6-dione 
• 93098-16-9 1,2-dihydro-5-(4-methoxyphenyl)-1-phenyl-6H-<1,2>diazepin-3,7-dione 
• 93098-15-8 1,2-dihydro-5-(4-methoxyphenyl)-7-methyl<1,2>diazepin-3-one 

Relevant articles and documents

Flexible Entry into 3-Arylpent-2-enedioic Acids via Heck-Matsuda Arylation of Dimethyl Glutaconate with Arenediazonium Tosylates

For the preparation of compound libraries of Michael acceptors with tunable reactivity toward nuclophilic selenocysteine residue of thioredoxin reductase, a range of 3-arylglutaconic acids were required. The existing methods at the time had limited scope or involved several steps. A hitherto undescribed protocol for direct palladium(II) acetate-catalyzed arylation of glutaconic acid dimethyl ester at position 3 has been developed with a diverse set of arenediazonium tosylates followed by hydrolysis. This generally good-yielding two-step sequence displayed a propensity to deliver E -configured coupling products while compounds mostly featured in the literature were predominantly Z -configured. The possibility for preparing a library of 4-arylpyridine-2,6(1 H,3 H)-diones has been exemplified.

A REINVESTIGATION OF THE SYNTHESIS OF 1,2-DIHYDRODIAZEPIN-3-ONES FROM PYRONES

The reactions of 5-acetyl-6-hydroxy-4-(4-methoxyphenyl)-2H-pyran-2-one (5) and 4-(4-methoxyphenyl)-2H-pyran-2,6-dione (4) with hydrazine and phenylhydrazine respectively, gave the respective 1-amino-2-pyridones 8 and 11 rather than diazepinones 6 and 10,