107049-57-0

Basic information

• Product Name: 1-(3,4,5-Trimethoxy-benzyl)-piperazinedihydrochloride
• Synonyms: 1-(3,4,5-Trimethoxy-benzyl)-piperazinedihydrochloride;1-[(3,4,5-trimethoxyphenyl)methyl]piperazine:dihydrochloride
• CAS NO: 107049-57-0
• Molecular Formula: C₁₄H₂₂N₂O₃*2ClH
• Molecular Weight: 339.25796
• Mol File: 107049-57-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3,4,5-Trimethoxy-benzyl)-piperazinedihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4,5-Trimethoxy-benzyl)-piperazinedihydrochloride(107049-57-0)
• EPA Substance Registry System: 1-(3,4,5-Trimethoxy-benzyl)-piperazinedihydrochloride(107049-57-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 107049-57-0(Hazardous Substances Data)

Usage

Description

1-(3,4,5-Trimethoxy-benzyl)-piperazine dihydrochloride, a white crystalline solid, is a chemical compound belonging to the class of piperazine derivatives. It is soluble in water and has been studied for its potential pharmaceutical applications, including its use as an antipsychotic and anticonvulsant. Additionally, it is being investigated for its potential to modulate dopamine receptor activity. The presence of the dihydrochloride salt in the compound increases its solubility and stability, making it suitable for use in pharmaceutical formulations.

Uses

Used in Pharmaceutical Industry:
1-(3,4,5-Trimethoxy-benzyl)-piperazine dihydrochloride is used as an active pharmaceutical ingredient for its potential antipsychotic and anticonvulsant properties. Its ability to modulate dopamine receptor activity makes it a promising candidate for the treatment of various psychiatric and neurological disorders.
Used in Research and Development:
In the field of research and development, 1-(3,4,5-Trimethoxy-benzyl)-piperazine dihydrochloride is used as a chemical probe to study the mechanisms of action and potential therapeutic effects of piperazine derivatives on the central nervous system. This helps in the development of new drugs and therapies for various conditions.
Used in Drug Formulation:
Due to its increased solubility and stability, 1-(3,4,5-Trimethoxy-benzyl)-piperazine dihydrochloride is used as a key component in the formulation of pharmaceutical products. This enhances the bioavailability and effectiveness of the drug, making it more suitable for clinical use.

Upstream product

• 110-85-0 piperazine 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Downstream Products

• 113720-99-3 1-(2,4-dichlorobenzoylethyl)-4-(3,4,5-trimethoxybenzyl)piperazine dihydrochloride 
• 123947-49-9 1-(1,4-benzodioxan-6-ylcarbonyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119035-25-5 1-(7-methoxyethoxy-1,2-dihydro-3-naphthoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119034-35-4 1-(7,8-dimethoxy-1,2-dihydro-4-naphthoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119034-55-8 1-(6,7-dibenzyloxy-1,2-dihydro-3-naphthoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119034-56-9 1-(7-benzyloxy-1,2-dihydro-3-naphthoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119035-22-2 1-(1-oxo-1,2,3,4-tetrahydro-6-naphthoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 
• 119034-54-7 1-(2-anthraquinonylcarbonyl)-4-(3,4,5-trimethoxybenzyl)piperazine 
• 119034-65-0 1-(9-oxo-2-fluorenylcarbonyl)-4-(3,4,5-trimethoxybenzyl)piperazine 
• 123947-30-8 1-(3,4-dimethoxybenzoyl)-4-(3,4,5-trimethoxybenzyl)piperazine hydrochloride 

Relevant articles and documents

Benzylpiperazine derivatives. II. Syntheses and cerebral vasodilating activities of 1-[(3-alkyl-3-hydroxy-3-phenyl)propyl]-4-benzylpiperazine derivatives

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