107096-11-7

Basic information

• Product Name: Furo[3,2-b]pyridine,3-methyl-(9CI)
• Synonyms: Furo[3,2-b]pyridine,3-methyl-(9CI)
• CAS NO: 107096-11-7
• Molecular Formula: C8H7NO
• Molecular Weight: 133.14728
• Product Categories: PYRIDINE
• Mol File: 107096-11-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Furo[3,2-b]pyridine,3-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,2-b]pyridine,3-methyl-(9CI)(107096-11-7)
• EPA Substance Registry System: Furo[3,2-b]pyridine,3-methyl-(9CI)(107096-11-7)

Safety Data

• Hazardous Substances Data: 107096-11-7(Hazardous Substances Data)

Upstream product

• 107096-08-2 ethyl 2-(2-acetyl-3-pyridyloxy)acetate 
• 107096-10-6 3-methylfuro<3,2-b>pyridine-2-carboxylic acid, ethyl ester 
• 107096-06-0 3-Methoxymethoxy-pyridine-2-carboxylic acid ethyl ester 
• 13210-29-2 1-(3-hydroxypyridin-2-yl)ethan-1-one 
• 73406-50-5 ethyl 3-hydroxypyridine-2-carboxylate 
• 874-24-8 3-hydroxypyridine-2-carboxylic acid 
• 167420-49-7 2-(3-furo<3,2-b>pyridyl)acetic acid 
• 107096-09-3 3-methyl-furo[3,2-b]-pyridine-2-carboxylic acid 

Relevant articles and documents

Furopyridines. XV. Synthesis and properties of ethyl 2-(3-furo[2,3-b]-, -[3,2-b]-, -[2,3-c]- and -[3,2-c]pyridyl)acetate

Ethyl 2-(3-furopyridyl)acetates 10a-d were synthesized from furopyridin-3(2H)-ones 4a-d by the Wittig-Horner reaction with diethyl cyanomethylphosphonate, hydrolysis and the subsequent esterification. Reaction of compounds 10a-d with lithium diisopropylamide (LDA) gave the corresponding methylene-lithiated intermediate, and the subsequent reaction with benzaldehyde, acetone and iodomethane afforded the methylene-alkylated product respectively, while N,N-dimethylacetamide did not give any reaction product. The 2-position of 10a, b and d is alkylated by the lithiation with excess of LDA and the successive reaction with an electrophile.