1072929-03-3

Basic information

• Product Name: 3-chloro-N-(4-chlorophenyl)-5-(1-propyl-1H-benzo[d]imidazol-2-yl)pyridin-2-amine
• CAS NO: 1072929-03-3
• Molecular Weight: 397.307
• Mol File: 1072929-03-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-chloro-N-(4-chlorophenyl)-5-(1-propyl-1H-benzo[d]imidazol-2-yl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-N-(4-chlorophenyl)-5-(1-propyl-1H-benzo[d]imidazol-2-yl)pyridin-2-amine(1072929-03-3)
• EPA Substance Registry System: 3-chloro-N-(4-chlorophenyl)-5-(1-propyl-1H-benzo[d]imidazol-2-yl)pyridin-2-amine(1072929-03-3)

Safety Data

• Hazardous Substances Data: 1072929-03-3(Hazardous Substances Data)

Upstream product

• 942511-67-3 5-chloro-6-(4-chlorophenylamino)nicotinic acid 
• 55899-42-8 N-propylbenzene-1,2-diamine 
• 41667-95-2 5,6-dichloronicotinic acid 
• 106-47-8 4-chloro-aniline 

Relevant articles and documents

Benzimidazoles as potent and orally active mGlu5 receptor antagonists with an improved pk profile

A focused chemical optimization effort of compound 1 based on metabolite elucidation is described, resulting in 15i, a highly potent and selective mGlu5 receptor antagonist with an improved pharmacokinetic profile compared to 1. Characterization of 15i in

NICOTINIC ACID DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5

The present invention relates to novel benzimidazole derivatives, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them, wherein the compounds have the Formula (I): in which the substitutents are as defined in claim 1 and and salts, solvates, hydrates and N- oxides thereof.