1072945-06-2 Usage
General Description
4-METHYL-3-NITROPHENYLBORONIC ACID, PINACOL ESTER is a chemical compound with the molecular formula C14H19BNO5. It is a boronic acid derivative that is commonly used in organic synthesis and chemical research. 4-METHYL-3-NITROPHENYLBORONIC ACID, PINACOL ESTER has a methyl group and a nitro group attached to a phenyl ring, and is in the pinacol ester form. It is often utilized as a reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds, and in other transformations in organic chemistry. Additionally, this compound has potential applications in pharmaceutical research and the development of new drugs. Overall, 4-METHYL-3-NITROPHENYLBORONIC ACID, PINACOL ESTER is a versatile chemical that plays a valuable role in the field of organic synthesis and chemical biology.
Check Digit Verification of cas no
The CAS Registry Mumber 1072945-06-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,9,4 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1072945-06:
(9*1)+(8*0)+(7*7)+(6*2)+(5*9)+(4*4)+(3*5)+(2*0)+(1*6)=152
152 % 10 = 2
So 1072945-06-2 is a valid CAS Registry Number.
InChI:InChI=1S/C13H18BNO4/c1-9-6-7-10(8-11(9)15(16)17)14-18-12(2,3)13(4,5)19-14/h6-8H,1-5H3
1072945-06-2Relevant articles and documents
Miyaura Borylation and One-Pot Two-Step Homocoupling of Aryl Chlorides and Bromides under Solvent-Free Conditions
Dzhevakov, Pavel B.,Topchiy, Maxim A.,Zharkova, Daria A.,Morozov, Oleg S.,Asachenko, Andrey F.,Nechaev, Mikhail S.
, p. 977 - 983 (2016)
Solvent-free protocols for Miyaura borylation and the one-pot, two-step homocoupling of aryl halides are reported for the first time. Bis(dibenzylideneacetone)palladium(0) [Pd(dba)2] is an optimal source of palladium for Miyaura borylation, while for one-pot two-step homocoupling palladium(II) acetate [Pd(OAc)2] gives highest yields. Aryl bromides are coupled most efficiently using the DPEphos ligand. Chlorides are coupled using XPhos. The developed protocols are robust, versatile and easily reproducible on a large scale.
Iron catalysis and water: A synergy for refunctionalization of boron
Wood, John L.,Marciasini, Ludovic D.,Vaultier, Michel,Pucheault, Mathieu
supporting information, p. 551 - 555 (2014/03/21)
A new catalytic system has been optimized to promote the conversion of boron species into others. FeCl3 associated with imidazole and water favors boron refunctionalization under mild conditions. Georg Thieme Verlag Stuttgart New York.
