80500-27-2 Usage
Description
4-Methyl-3-nitrophenylboronic acid is an organic compound that serves as a versatile building block in organic synthesis. It is a white to light yellow crystal powder with unique chemical properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
4-Methyl-3-nitrophenylboronic acid is used as a reactant for the preparation of inhibitors of lactate dehydrogenase, which helps in combating cancer cell proliferation. Its ability to target key enzymes involved in cancer metabolism makes it a valuable component in the development of potential anti-cancer drugs.
Used in Organic Synthesis:
4-Methyl-3-nitrophenylboronic acid is used as a reactant in Suzuki-Miyaura coupling reactions, a widely employed method for the formation of carbon-carbon bonds. This reaction is crucial in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials.
Used in Thyroid Research:
4-Methyl-3-nitrophenylboronic acid is used as a reactant for the preparation of imidazothiazoles, which act as iodide efflux inhibitors in thyrocytes. These compounds are essential in studying the role of iodide transport in thyroid function and can potentially lead to the development of treatments for thyroid-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 80500-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,0 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 80500-27:
(7*8)+(6*0)+(5*5)+(4*0)+(3*0)+(2*2)+(1*7)=92
92 % 10 = 2
So 80500-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H8BNO4/c1-5-2-3-6(8(10)11)4-7(5)9(12)13/h2-4,10-11H,1H3
80500-27-2Relevant articles and documents
Iron trichloride promoted hydrolysis of potassium organotrifluoroborates
Blevins, David W.,Yao, Min-Liang,Yong, Li,Kabalka, George W.
experimental part, p. 6534 - 6536 (2011/12/22)
In the presence of iron trichloride, the hydrolysis of potassium organotrifluoroborates occurs smoothly at room temperature to afford the corresponding organoboronic acids in good to excellent yields. The hydrolysis is effective for aryltrifluoroborates as well as alkenyl- and alkyl- trifluoroborates.
