107462-36-2

Basic information

• Product Name: Benzenepropanamide, a-(dimethylamino)-N-[(3S,4S,7S,11R)-11-hydroxy-3-(1-methylethyl)-7-(2-methylpropyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14,15-trien-4-yl]-,(aS)-
• Synonyms: Benzenepropanamide,a-(dimethylamino)-N-[11-hydroxy-3-(1-methylethyl)-7-(2-methylpropyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14,15-trien-4-yl]-,[3S-[3R*,4R*(R*),7R*,11S*]]-; 2-Oxa-6,9-diazabicyclo[10.2.2]hexadecane, benzenepropanamidederiv.; (-)-Sanjoinine G1; Sanjoinine G1
• CAS NO: 107462-36-2
• Molecular Formula: C31H44 N4 O5
• Molecular Weight: 552.714
• Mol File: 107462-36-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, a-(dimethylamino)-N-[(3S,4S,7S,11R)-11-hydroxy-3-(1-methylethyl)-7-(2-methylpropyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14,15-trien-4-yl]-,(aS)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, a-(dimethylamino)-N-[(3S,4S,7S,11R)-11-hydroxy-3-(1-methylethyl)-7-(2-methylpropyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14,15-trien-4-yl]-,(aS)-(107462-36-2)
• EPA Substance Registry System: Benzenepropanamide, a-(dimethylamino)-N-[(3S,4S,7S,11R)-11-hydroxy-3-(1-methylethyl)-7-(2-methylpropyl)-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14,15-trien-4-yl]-,(aS)-(107462-36-2)

Safety Data

• Hazardous Substances Data: 107462-36-2(Hazardous Substances Data)

Upstream product

• 136898-42-5 [3S,4S,7S,11R]-(11-hydroxy-7-isobutyl-3-isopropyl-5,8-dioxo-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-4-yl)-carbamic acid tert-butyl ester 
• 171618-25-0 (2S,3S)-3-{4-[2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-acetyl]-phenoxy}-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 
• 171618-20-5 4-[(1S,2R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-1-isopropyl-propoxy]-benzoic acid methyl ester 
• 171618-19-2 tert-butyl ((2R,3R)-1-((tert-butyldimethylsilyl)oxy)-3-hydroxy-4-methylpentan-2-yl)carbamate 
• 214900-86-4 (2S,3S)-3-{4-[2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-1-hydroxy-ethyl]-phenoxy}-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid pentafluorophenyl ester 
• 2018-66-8 Z-Leu-OH 
• 221004-74-6 Acetic acid (3S,4S,7S,11R)-4-dibenzylamino-7-isobutyl-3-isopropyl-14-nitro-5,8-dioxo-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-11-yl ester 
• 87421-21-4 (2S,3S)-3-hydroxyleucine methyl ester 
• 10148-70-6 (2S,3S)-3-hydroxyleucine 
• 221004-69-9 (2S,3S)-2-Dibenzylamino-3-hydroxy-4-methyl-pentanoic acid {(S)-1-[(R)-2-(4-fluoro-3-nitro-phenyl)-2-hydroxy-ethylcarbamoyl]-3-methyl-butyl}-amide 
• 221004-73-5 (3S,4S,7S,11R)-4-Dibenzylamino-11-hydroxy-7-isobutyl-3-isopropyl-14-nitro-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-triene-5,8-dione 
• 221004-75-7 Acetic acid (3S,4S,7S,11R)-4-dibenzylamino-7-isobutyl-3-isopropyl-5,8-dioxo-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-11-yl ester 
• 221004-70-2 (2S,3S)-2-Dibenzylamino-3-hydroxy-4-methyl-pentanoic acid pentafluorophenyl ester 
• 221004-68-8 Acetic acid (3S,4S,7S,11R)-4-amino-7-isobutyl-3-isopropyl-5,8-dioxo-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-11-yl ester 

Downstream Products

• 221004-76-8 O-Ac-sanjoinine G₁ 

Relevant articles and documents

A convergent approach to cyclopeptide alkaloids: Total synthesis of sanjoinine G1

A general strategy for the synthesis of cyclopeptide alkaloids containing an endocyclic aryl-alkyl ether bond has been developed featuring a key intramolecular SNAr reaction. The importance of the N-terminal protective group in the realization

Total synthesis of the cyclopeptide alkaloid sanjoinine G1 and its C-11 epimer

The naturally occurring cyclopeptide alkaloid sanjoinine G1 and its C- 11 epimer were synthesized in 18 steps from D-serine. The key steps in the synthesis were the formation of the alkylaryl ether linkage via an S(N)Ar reaction with 4-fluorobenzonitrile