1075-05-4

Basic information

• Product Name: threo-1-Phenyl-1,2-dihydroxypropan
• Synonyms: threo-1-Phenyl-1,2-dihydroxypropan
• CAS NO: 1075-05-4
• Molecular Weight: 152.193
• Mol File: 1075-05-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: threo-1-Phenyl-1,2-dihydroxypropan(CAS DataBase Reference)
• NIST Chemistry Reference: threo-1-Phenyl-1,2-dihydroxypropan(1075-05-4)
• EPA Substance Registry System: threo-1-Phenyl-1,2-dihydroxypropan(1075-05-4)

Safety Data

• Hazardous Substances Data: 1075-05-4(Hazardous Substances Data)

Upstream product

• 4436-22-0 1-phenylpropylene oxide 
• 1798-60-3 (R)-1-hydroxy-1-phenyl-2-propanone 
• 5650-40-8 (S)-2-hydroxypropiophenone 
• 37580-42-0 (E)-2-methyl-1-phenyl-1,3-butadiene 
• 1333259-97-4 (S,Z)-2-methyl-1-phenylbut-2-ene-1,4-diol 
• 827608-92-4 (S)-4,4,5,5-tetramethyl-2-(1-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-2-en-2-yl)-1,3,2-dioxaborolane 
• 2327-99-3 1-phenylpropadiene 
• 98819-68-2 3-phenyl-(2R,3R)-oxiran-2-ylmethanol 
• 25438-37-3 phenyl(trimethylsiloxy)acetonitrile 
• 93-54-9 1-Phenyl-1-propanol 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 103687-21-4 ((CH₃)3C₆H₂)2BCHLiCH₃ 
• 100-52-7 benzaldehyde 
• 637-50-3 1-phenylpropene 

Downstream Products

• 123485-24-5 (1R,2S)-1,2-diacetoxy-1-phenylpropane 
• 123485-25-6 (1R,2R)-1,2-diacetoxy-1-phenylpropane 
• 123485-26-7 (1S,2R)-1,2-diacetoxy-1-phenylpropane 
• 159992-91-3 2,2,4-trimethyl-5-phenyldioxolan 
• 159992-92-4 2,2,4-trimethyl-5-phenyldioxolan 
• 40421-52-1 (1R,2S)-1-phenylpropane-1,2-diol 
• 40421-51-0 (1R,2R)-1-phenylpropane-1,2-diol 
• 88196-06-9 (1S,2S)-1-phenyl-1,2-propanediol 

Relevant articles and documents

OsO4?streptavidin: A tunable hybrid catalyst for the enantioselective cis-dihydroxylation of olefins

Taking control: Selective catalysts for olefin dihydroxylation have been generated by the combination of apo-streptavidin and OsO4. Site-directed mutagenesis allows improvement of enantioselectivity and even inversion of enantiopreference in certain cases. Notably allyl phenyl sulfide and cis-β-methylstyrene were converted with unprecedented enantiomeric excess.

Hot water-promoted ring-opening of epoxides and aziridines by water and other nucleopliles

Effective hydrolysis of epoxides and aziridines was conducted by heating them in water at 60 or 100 °C. Other types of nucleophile such as amines, sodium azide, and thiophenol could also efficiently open epoxides and aziridines in hot water. It was proposed that hot water acted as a modest acid catalyst, reactant, and solvent in the hydrolysis reactions.

Hindered organoboron groups in organic chemistry. 23. The interactions of dimesitylboron stabilised carbanions with aromatic ketones and aldehydes to give alkenes

Dimesitylboron stabilised carbanions react with diarylketones to give the corresponding alkenes in mild conditions with good yields. Reactions with aromatic aldehydes are more complex, but in all cases E-alkenes are available in good yields by trapping the intermediates with chlorotrimethylsilane followed by treatment with aq. HF/CH3CN. Treatment of the same intermediates with trifluoroacetic anhydride gives mainly the Z-alkenes. The design and mechanisms of these important processes are considered.