107750-95-8

Basic information

• Product Name: 4-phenyl-2-(phenylthio)-1H-imidazole
• Synonyms: 4-phenyl-2-(phenylthio)-1H-imidazole
• CAS NO: 107750-95-8
• Molecular Weight: 252.34
• Mol File: 107750-95-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-phenyl-2-(phenylthio)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-2-(phenylthio)-1H-imidazole(107750-95-8)
• EPA Substance Registry System: 4-phenyl-2-(phenylthio)-1H-imidazole(107750-95-8)

Safety Data

• Hazardous Substances Data: 107750-95-8(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 6857-34-7 2-mercapto-4⁽⁵⁾-phenylimidazole 
• 70-11-1 α-bromoacetophenone 
• 108-86-1 bromobenzene 
• 25752-18-5 6-phenylimidazo[2,1-b]-1,3,4-thiadiazole 
• 591-51-5 phenyllithium 
• 4335-28-8 2,3-diidro-6-fenilimidazo<2,1-b>tiazolo 
• 107750-92-5 4-Phenyl-2-phenylsulfanyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole 

Relevant articles and documents

Mild ligand-free Cu0-catalyzed chemoselective S-arylation of 2-mercaptoimidazole at low catalyst loading

A mild method for the Cu0-catalyzed chemoselective C[sbnd]S cross-coupling of 2-mercaptoimidazole derivatives with a series of with differently substituted iodobenzenes and iodothiophenes at 100 °C is described. This method proceeds efficiently without ligands and at low catalyst loading (3 mol %), without the need for stringent inert conditions. Under optimized conditions, the S-arylated products were obtained in good yields of up to 90%.

Unexpected reactivity of imidazo[2,1-b]thiazolines with organometallic reagents

The reaction of imidazo[2,1-b]thiazolines with various organometallic reagents is described. Nucleophilic attack of organolithium reagents on sulfur occurs with extrusion of ethylene to produce 2-thioalkyl-or 2-thioarylimidazoles. The outcome with Grignar