4335-28-8

Basic information

• Product Name: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE
• Synonyms: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE;6-PHENYL-2,3-DIHYDRO-IMIDAZO[2,1-B]THIAZOLE;BUTTPARK 4\01-71;6-Phenyl-2,3-dihydro1midazo[2,1-b][1,3]thiazole;2,3-Dihydro -6-phenyl-imidazo[2,1-b]thiazole Hydrochloride;Levamisole EP Impurity D
• CAS NO: 4335-28-8
• Molecular Formula: C₁₁H₁₀N₂S
• Molecular Weight: 202.28
• Mol File: 4335-28-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 147 °C
• Appearance: /
• CAS DataBase Reference: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE(4335-28-8)
• EPA Substance Registry System: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE(4335-28-8)

Safety Data

• Hazardous Substances Data: 4335-28-8(Hazardous Substances Data)

Usage

Description

6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE is a chemical compound that is derived from the degradation of levamisole, which is an anthelmintic agent. 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE is characterized by its unique imidazothiazole structure with a phenyl group attached at the 6th position.

Uses

Used in Pharmaceutical Industry:
6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE is used as an intermediate compound in the synthesis of various pharmaceutical products. Its presence as a degradation product of levamisole, an anthelmintic, suggests potential applications in the development of new anthelmintic drugs or other therapeutic agents.
Used in Research and Development:
In the field of research and development, 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE can be utilized as a starting material or a building block for the creation of novel chemical entities with potential biological activities. Its unique structure may offer new insights into the design of drugs targeting various diseases and conditions.
Used in Chemical Synthesis:
6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE can also be employed as a reactant in various chemical synthesis processes, allowing for the development of new compounds with diverse applications across different industries, such as agriculture, materials science, and environmental science.

Upstream product

• 1779-81-3 4,5-Dihydro-thiazol-2-ylamin 
• 70-11-1 α-bromoacetophenone 
• 4335-26-6 2-(2-imino-thiazolidin-3-yl)-1-phenyl-ethanone; hydrobromide 

Downstream Products

• 115859-04-6 5-<1-(ethoxycarbonyl)-1,4-dihydro-4-pyridyl>-6-phenylimidazo<2,1-b>thiazoline 
• 75224-64-5 2,3-diidro-5-formil-6-fenilimidazo<2,1-b>tiazolo 
• 107750-95-8 4-phenyl-2-(phenylthio)-1H-imidazole 
• 301857-39-6 2-butylmercapto-4-phenyl-1⁽³⁾H-imidazole 
• 25433-10-7 2-(methylthio)-4-phenyl-1H-imidazole 
• 96439-70-2 4-phenyl-2-thioxo-1-vinyl-4-imidazoline 
• 53704-77-1 1-benzyl-4-phenyl-1H-imidazole 

Relevant articles and documents

Synthetic and Mechanistic Studies on the Preparation of Pyridyl-Substituted Imidazothiazoles

A new method is presented for the introduction of the 4'-pyridyl substituent into 6-aryl-2,3-dihydroimidazothiazoles.The method involves treatment of the imidazothiazolines with the reactive complex of pyridine and ethyl chloroformate and oxidative deethyl carboxylation of the dihydropyridine adducts formed.Sulfur in refluxing mesitylene was found most suitable for the latter reaction, but chromium trioxide in pyridine or KtBuO and air were also effective.