108054-70-2

Basic information

• Product Name: 2-(4-chlorophenylsulphonyloxymethyl)-5,5-dimethyl-1,3,2-dioxaphosphorinan
• CAS NO: 108054-70-2
• Molecular Weight: 354.748
• Mol File: 108054-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenylsulphonyloxymethyl)-5,5-dimethyl-1,3,2-dioxaphosphorinan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenylsulphonyloxymethyl)-5,5-dimethyl-1,3,2-dioxaphosphorinan(108054-70-2)
• EPA Substance Registry System: 2-(4-chlorophenylsulphonyloxymethyl)-5,5-dimethyl-1,3,2-dioxaphosphorinan(108054-70-2)

Safety Data

• Hazardous Substances Data: 108054-70-2(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 873-99-4 5,5-dimethyl-2-hydroxy-2-oxo-1,3,2-dioxaphosphorinane 

Downstream Products

• 108054-71-3 2-benzyloxy-6,6-dimethyl-1,4,2-dioxaphosphepan-2-one 
• 108054-72-4 benzyl 3-hydroxy-2,3-dimethylpropoxymethylphosphonate 

Relevant articles and documents

Synthesis of Diethyl Alkoxymethylphosphonates via Lewis Acid Promoted Regiospecific Cleavage of Alkoxy-4-Chlorophenoxymethanes

Alkoxy-4-chlorophenoxymethanes, readily prepared from 1-chloro-4-chloromethoxybenzene and sodium alkoxide, generate alkoxymethyltriethoxyphosphonium ions in a regiospecific reaction with triethyl phosphite and titanium tetrachloride or boron trifluoride.Precise reaction conditions are necessary since the phosphonium ions can undergo disproportionation.Subsequent addition of water gives diethyl alkoxymethylphosphonates; if disproportionation has been permitted these contain 4-chlorophenyl ethyl alkoxymethylphosphonates.Under the preferred conditions (titanium tetrachloride, -78 deg C, 15 min, dichloromethane) yields of ca. 80percent of diethylalkoxymethylphosphonates have been obtained from primary, secondary, tertiary, and allylic alcohols.