873-99-4

Basic information

• Product Name: 5,5-dimethyl-1,3,2-dioxaphosphinan-2-ol 2-oxide
• CAS NO: 873-99-4
• Molecular Formula: C₅H₁₁O₄P
• Molecular Weight: 166.1122
• Mol File: 873-99-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 218.5°C at 760 mmHg
• Flash Point: 85.9°C
• Density: 1.28g/cm³
• Vapor Pressure: 0.0476mmHg at 25°C
• Refractive Index: 1.451
• CAS DataBase Reference: 5,5-dimethyl-1,3,2-dioxaphosphinan-2-ol 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-1,3,2-dioxaphosphinan-2-ol 2-oxide(873-99-4)
• EPA Substance Registry System: 5,5-dimethyl-1,3,2-dioxaphosphinan-2-ol 2-oxide(873-99-4)

Safety Data

• Hazardous Substances Data: 873-99-4(Hazardous Substances Data)

Upstream product

• 4090-55-5 2-chloro-5,5-dimethyl[1,3,2]dioxaphosphinane 2-oxide 
• 97533-81-8 (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-hydrazine 
• 75-65-0 tert-butyl alcohol 
• 132868-54-3 2-N-benzoyl-N-phenylamino-2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane 
• 80-15-9 Cumene hydroperoxide 
• 128851-21-8 3-(5,5-Dimethyl-[1,3,2]dioxaphosphinan-2-yloxy)-butan-2-one 
• 24423-87-8 3,4-dihydro-isoquinoline 2-oxide 
• 67889-05-8 2-<(ethoxycarbonyl)methyl>-2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane 
• 64-17-5 ethanol 
• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 

Downstream Products

• 1369964-86-2 2-(((5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)oxy)methyl)-3-phenyl-4H-thiochromen-4-one 1,1-dioxide 
• 108054-70-2 2-(4-chlorophenylsulphonyloxymethyl)-5,5-dimethyl-1,3,2-dioxaphosphorinan 
• 108054-72-4 benzyl 3-hydroxy-2,3-dimethylpropoxymethylphosphonate 
• 108054-71-3 2-benzyloxy-6,6-dimethyl-1,4,2-dioxaphosphepan-2-one 

Relevant articles and documents

Rate and product studies in the solvolyses of two cyclic phosphorochloridate esters

Kinetic and product studies of the solvolyses of acyclic phosphorochloridates are extended to two cyclic diesters, 2-chloro-1,3,2- dioxaphospholane-2-oxide (1) and 2-chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane- 2-oxide (2). Slightly faster solvolyses are observed for 1 than for the acyclic dimethyl phosphorochloridate (3), and 2 solvolyzes somewhat slower than 3. An extended Grunwald-Winstein equation treatment shows similar sensitivities to changes in solvent nucleophilicity and solvent ionizing power for 1, 2, and 3, and a concerted SN2 attack is proposed in each case. Product studies for the solvolyses of 2 in aqueous alcohols are presented. [image presented]. Copyright Taylor & Francis Group, LLC.

Reaction mechanism studies of solvolytic displacement of chloride from phosphorus

The extended Grunwald-Winstein equation is applied to solvolytic displacement at phosphorus. Previous studies of the solvolyses of phosphorochloridates (RO)2POCl, Ph2POCl and [(CH3)2N]2POCl are extended to cyclic phosphorochloridates, with five and six me

Phosphorochloridates from phosphorohydrazides with ButOCl: Stereospecificity, selectivity and phosphorylium ion intermediates

The efficiency with which a six-membered cyclic phosphorochloridate can be obtained from the corresponding hydrazide with retention of configuration at phosphorus, using tert-butyl hypochlorite in tert-butyl alcohol, depends on how stereoelectronic factors influence the fate of an intermediate chloride-phosphorylium ion pair.