1083326-46-8 Usage
Description
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide is a chemical compound that features a pyrazole core with a tetramethyl-1,3,2-dioxaborolan-2-yl group attached to the 4-position. 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide is characterized by its potential reactivity and stability, making it a valuable intermediate in the synthesis of various pharmaceutical and biologically active compounds.
Uses
Used in Pharmaceutical Industry:
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide is used as a key intermediate in the synthesis of pharmaceutical compounds for the development of inhibitors and therapeutic agents. Its unique structure allows for the creation of novel drug candidates with potential applications in treating various diseases and conditions.
Used in Biological Research:
In the field of biological research, 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide serves as a valuable tool for the design and synthesis of biologically active molecules. Its versatility in chemical reactions enables the exploration of new chemical space and the discovery of innovative therapeutic agents with improved efficacy and selectivity.
Used in Drug Discovery:
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide is utilized in drug discovery processes to create new chemical entities with potential therapeutic benefits. Its incorporation into drug candidates can lead to the development of more effective treatments for a wide range of medical conditions, including cancer, inflammatory diseases, and infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1083326-46-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,3,3,2 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1083326-46:
(9*1)+(8*0)+(7*8)+(6*3)+(5*3)+(4*2)+(3*6)+(2*4)+(1*6)=138
138 % 10 = 8
So 1083326-46-8 is a valid CAS Registry Number.
1083326-46-8Relevant articles and documents
DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0286; 0287, (2016/08/23)
The present invention discloses a novel DGAT1 inhibitor, especially the compound of formula (I) or a pharmaceutically acceptable salt thereof, preparation and pharmaceutical composition thereof, as well as their uses in the preparation of a medicament for the prevention and treatment of Familial hyperchylomicronemia (FCS), obesity, hyperlipoproteinemia or hypertriglyceridemia.
P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS
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Paragraph 0222; 0223, (2015/07/07)
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.
5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS
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Page/Page column 160, (2009/01/24)
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.