1084-95-3Relevant articles and documents
Cobalt(II)-Catalyzed Csp2-H Alkynylation/Annulation with Terminal Alkynes: Selective Access to 3-Methyleneisoindolin-1-one
Zhang, Lin-Bao,Hao, Xin-Qi,Liu, Zhan-Jiang,Zheng, Xin-Xiang,Zhang, Shou-Kun,Niu, Jun-Long,Song, Mao-Ping
, p. 10012 - 10015 (2015)
A highly efficient cobalt(II)-catalyzed alkynylation/annulation of terminal alkynes assisted by an N,O-bidentate directing group is described. This protocol is characterized by wide substrate scope utilizing cheap cobalt catalysts, and offers a new approa
Use of Imidazo[1,5-a]pyridin-3-ylidene as a Platform for Metal-Imidazole Cooperative Catalysis: Silver-Catalyzed Cyclization of Alkyne-Tethered Carboxylic Acids
Rawat, Vishal Kumar,Higashida, Kosuke,Sawamura, Masaya
supporting information, p. 1631 - 1637 (2021/02/03)
Silver complexes with 5-(4-(tert-butyl)-1H-imidazol-1-yl)-imidazo[1,5-a]pyridin-3-ylidene ligands were synthesized as metal-imidazole acid-base cooperative catalysts. Single crystal XRD analysis revealed that the silver atom was located in the vicinity of
Fe(III)-Catalyzed, Cyclizative Coupling between 2-Alkynylbenzoates and Carbinols: Rapid Generation of Polycyclic Isocoumarins and Phthalides and Mechanistic Study
Gandhi, Soniya,Baire, Beeraiah
, p. 2651 - 2657 (2020/05/25)
FeCl3 catalyzed, highly regioselective cyclizative coupling of internal alkynes with alcohols has been reported for the rapid synthesis of structurally divergent, complex isocoumarins and phthalides respectively in intermolecular and intramolecular fashion. This strategy exhibited very high substrate scope and efficiency and proceeds through the simultaneous formation of C?O and C?C bonds. Observations from a series of control experiments supported a) the mechanism as Lewis acid catalyzed dual activation of ester and alcohol, b) the role of carbocation for the enhanced rates of cyclization, i. e., activation of alkyne by carbocation, and c) no role of HCl in the reported cascade process. (Figure presented.).
Preparation method of 3-hydroxy-2,3-dihydroisoquinoline-1,4-dione compound
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Paragraph 0045; 0046; 0060; 0061, (2019/08/01)
The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method of a 3-hydroxy-2,3-dihydroisoquinoline-1,4-dione compound. In the preparation methodprovided by the invention, N-alkoxy-2-alkynyl benzamide