1087408-67-0Relevant articles and documents
Study of the Stability of O,O -Dialkyl- O -Arylthiophosphate: Evidence of the Formation of O,S -Dialkyl- O -Arylphosphate
Le Corre, Stéphanie S.,Fraix, Aurore,Berchel, Mathieu,Jaffrès, Paul-Alain
, p. 747 - 750 (2015)
During the synthesis of cationic lipids that included thiophosphoramidate moiety or pincer ligands based on O,O-diethyl-thiophosphonate as coordination group, the rearrangement of O,O-diethyl-thiophosphoryl in O,S-diethylthiophosphoryl group was observed. This rearrangement, which does not occur by a simple heating at 130°C, is catalyzed by nucleophilic amine like N,N-dimethylaminopyridine. However, at some occasion, dealkylation of the O,S-diethylthiophosphoryl compound is observed.