109050-30-8 Usage
Molar mass
231.04 g/mol The molar mass of the compound is the mass of one mole of the substance, and in this case, it is 231.04 grams per mole.
Fluoroacetic acid derivative
A fluoroacetic acid derivative is a compound that has a fluoroacetic acid functional group attached to another molecule. In 2-(4-Bromophenyl)-2-fluoroacetic acid, the 4-bromophenyl group is attached to the alpha carbon of the fluoroacetic acid moiety.
4-Bromophenyl group
This is a phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a bromine atom attached to the fourth carbon atom.
Alpha carbon
The alpha carbon is the carbon atom in a molecule that is adjacent to the functional group or the carbon chain to which the functional group is attached.
Potential building block for synthesis
2-(4-Bromophenyl)-2-fluoroacetic acid can be used as a starting material or intermediate in the synthesis of various pharmaceuticals and biologically active molecules due to its unique structural features.
Applications in organic synthesis and medicinal chemistry
The compound may be useful in the development of new organic synthesis methods and the creation of novel medicinal compounds.
Proper handling and storage precautions
As with any chemical, it is important to follow appropriate safety measures, such as wearing protective gear and storing the compound in a secure and appropriate environment, to ensure safe use and prevent accidents.
Check Digit Verification of cas no
The CAS Registry Mumber 109050-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,0,5 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 109050-30:
(8*1)+(7*0)+(6*9)+(5*0)+(4*5)+(3*0)+(2*3)+(1*0)=88
88 % 10 = 8
So 109050-30-8 is a valid CAS Registry Number.
109050-30-8Relevant articles and documents
Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
Sap, Jeroen B. I.,Wilson, Thomas C.,Kee, Choon Wee,Straathof, Natan J.W.,Ende, Christopher W.am,Mukherjee, Paramita,Zhang, Lei,Genicot, Christophe,Gouverneur, Véronique
, p. 3237 - 3241 (2019/03/21)
Herein, we report the radiosynthesis of 18F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [18F]fluoride. The two key steps are a copper-catalysed cross-coupling reaction, and a Mn-mediated 18F-fluorodecarboxylation.
Catalytic decarboxylative fluorination for the synthesis of Tri- and difluoromethyl arenes
Mizuta, Satoshi,Stenhagen, Ida S.R.,O'Duill, Miriam,Wolstenhulme, Jamie,Kirjavainen, Anna K.,Forsback, Sarita J.,Tredwell, Matthew,Sandford, Graham,Moore, Peter R.,Huiban, Mickael,Luthra, Sajinder K.,Passchier, Jan,Solin, Olof,Gouverneur, Véronique
supporting information, p. 2648 - 2651 (2013/07/11)
Treatment of readily available α,α-difluoro- and α-fluoroarylacetic acids with Selectfluor under Ag(I) catalysis led to decarboxylative fluorination. This operationally simple reaction gave access to tri- and difluoromethylarenes applying a late-stage fluorination strategy. Translation to [18F]labeling is demonstrated using [ 18F]Selectfluor bis(triflate), a reagent affording [ 18F]tri- and [18F]difluoromethylarenes not within reach with [18F]F2.
