109113-39-5

Basic information

• Product Name: 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine
• Synonyms: 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine;1-(Phenylsulfonyl)-5-azaindole
• CAS NO: 109113-39-5
• Molecular Formula: C₁₃H₁₀N₂O₂S
• Molecular Weight: 258.2957
• Mol File: 109113-39-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 124-125 °C
• Boiling Point: 480.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.14±0.30(Predicted)
• CAS DataBase Reference: 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine(109113-39-5)
• EPA Substance Registry System: 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine(109113-39-5)

Safety Data

• Hazardous Substances Data: 109113-39-5(Hazardous Substances Data)

Usage

General Description

1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine is a chemical compound with the molecular formula C13H9NO2S. It is a pyridine derivative that contains a phenylsulfonyl group, which is a functional group consisting of a phenyl group connected to a sulfonyl group (SO2). 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine has potential applications in medicinal chemistry and drug discovery due to its unique structure and the presence of the pyrrolopyridine core, which is a common pharmacophore in bioactive molecules. Its synthesis and reactivity have been studied in the context of developing new methods for constructing complex organic molecules, and it may have therapeutic potential as a drug candidate in the future. Additional research is needed to fully understand its biological and pharmacological properties.

Upstream product

• 271-34-1 5-azaindole 
• 98-09-9 benzenesulfonyl chloride 
• 148760-46-7 3-(4-Morpholinovinylene)-4-nitropyridine 1-oxide 
• 123367-22-6 (E)-N,N-dimethyl-2-(4-nitro-1-oxidopyridin-3-yl)ethenamine 
• 148760-47-8 3-Dimethylaminovinylene-4-nitropyridine 
• 1074-98-2 3-methyl-4-nitropyridine N-oxide 
• 1678-53-1 4-nitro-3-methylpyridine 

Downstream Products

• 60290-21-3 4-chloro-1H-pyrrolo-[3,2-c]-pyridine 
• 1257294-40-8 4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine 
• 209286-78-2 1-(benzenesulfonyl)-4-chloro-1H-pyrrolo[3,2-c]pyridine 
• 148729-73-1 2-(1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine)-4-(3-diethylaminocarbonyl-2-methoxypyridyl)-1,1-ethanol 
• 125335-95-7 2-(1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine)-4-(3-diethylaminocarbonyl-2-methoxypyridyl)ketone 
• 877060-46-3 1-benzenesulfonyl-1H-pyrrolo[3,2-c]pyridine-2-boronic acid 
• 109113-44-2 1-Benzenesulfonyl-2-formyl-1H-pyrrolo<3,2-c>pyridine 
• 877060-44-1 1-benzenesulfonyl-2-iodo-1H-pyrrolo[3,2-c]pyridine 

Relevant articles and documents

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF

7-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 7-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF

Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS

The present invention provides a heterocyclic compound having a TLR7, TLR9, TLR7/8, TLR7/9 or TLR7/8/9 inhibitory action, which is useful as an agent for the prophylaxis or treatment of autoimmune diseases, inflammatory diseases and the like, in particular, systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, psoriasis, inflammatory bowel disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.