209286-78-2

Basic information

• Product Name: 1-(Phenylsulfonyl)-4-chloro-5-azaindole
• Synonyms: 1-(Phenylsulfonyl)-4-chloro-5-azaindole
• CAS NO: 209286-78-2
• Molecular Formula: C13H9ClN2O2S
• Molecular Weight: 292.74076
• Mol File: 209286-78-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 510.0±53.0 °C(Predicted)
• Appearance: /
• Density: 1.45±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.98±0.30(Predicted)
• CAS DataBase Reference: 1-(Phenylsulfonyl)-4-chloro-5-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Phenylsulfonyl)-4-chloro-5-azaindole(209286-78-2)
• EPA Substance Registry System: 1-(Phenylsulfonyl)-4-chloro-5-azaindole(209286-78-2)

Safety Data

• Hazardous Substances Data: 209286-78-2(Hazardous Substances Data)

Usage

General Description

1-(Phenylsulfonyl)-4-chloro-5-azaindole is a chemical compound with the molecular formula C14H10ClN1O2S1. It is a sulfonyl-substituted azaindole derivative, which makes it useful for various pharmaceutical and agrochemical applications. The presence of a chloro group and a phenylsulfonyl group in its structure gives the compound unique properties that make it potentially valuable for diverse applications in medicinal chemistry and crop protection. It is important to handle and use this compound with caution as it may pose health and safety risks if not handled properly. Overall, 1-(Phenylsulfonyl)-4-chloro-5-azaindole is a versatile chemical with promising potential for various industrial and research applications.

Upstream product

• 60290-21-3 4-chloro-1H-pyrrolo-[3,2-c]-pyridine 
• 98-09-9 benzenesulfonyl chloride 
• 271-34-1 5-azaindole 
• 109113-39-5 1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine 

Relevant articles and documents

PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS

The present invention provides a heterocyclic compound having a TLR7, TLR9, TLR7/8, TLR7/9 or TLR7/8/9 inhibitory action, which is useful as an agent for the prophylaxis or treatment of autoimmune diseases, inflammatory diseases and the like, in particular, systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, psoriasis, inflammatory bowel disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF

4-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 4-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINES AND THERAPEUTIC USES THEREOF

6-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 6-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.