1092114-59-4

Basic information

• Product Name: 3-iodo-1H-indole-5-carbonitrile
• Synonyms: 3-iodo-1H-indole-5-carbonitrile
• CAS NO: 1092114-59-4
• Molecular Formula: C₉H₅IN₂
• Molecular Weight: 268.05387
• Mol File: 1092114-59-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-iodo-1H-indole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-iodo-1H-indole-5-carbonitrile(1092114-59-4)
• EPA Substance Registry System: 3-iodo-1H-indole-5-carbonitrile(1092114-59-4)

Safety Data

• Hazardous Substances Data: 1092114-59-4(Hazardous Substances Data)

Usage

General Description

3-Iodo-1H-indole-5-carbonitrile is a chemical compound with the molecular formula C9H5IN2. It is a derivative of indole, which is an aromatic heterocyclic organic compound. 3-iodo-1H-indole-5-carbonitrile is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has been found to have potential applications in the field of medicinal chemistry, particularly in the development of anticancer and antiviral drugs. Its molecular structure and properties make it a useful starting material in organic synthesis for the preparation of various functionalized indole derivatives. The presence of the iodine and cyano groups in this compound also gives it the potential to exhibit interesting biological activities, making it a subject of interest for further research in the fields of drug discovery and development.

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 

Downstream Products

• 1401349-98-1 N-(3-(3-iodo-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-yl)acetamide 
• 1401349-97-0 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-isopropyl-1,2,4-oxadiazol-5-amine 
• 1401349-96-9 3-(3-iodo-1-tosyl-1H-indol-5-yl)-N-isopropyl-1,2,4-oxadiazol-5-amine 
• 1401349-95-8 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-methyl-1,2,4-oxadiazol-5-amine 
• 1401349-94-7 3-(3-iodo-1-tosyl-1H-indol-5-yl)-N-methyl-1,2,4-oxadiazol-5-amine 
• 1401349-93-6 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-91-4 3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-90-3 3-(3-(6-isopropoxypyridin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-89-0 3-(3-iodo-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-88-9 3-(3-iodo-1-tosyl-1H-indol-5-yl)-5-(trichloromethyl)-1,2,4-oxadiazole 
• 1401349-87-8 N'-hydroxy-3-iodo-1-tosyl-1H-indole-5-carboximidamide 
• 864685-26-7 tert-butyl 5-cyano-3-iodo-1H-indole-1-carboxylate 
• 676273-39-5 3-iodo-1-tosyl-1H-indole-5-carbonitrile 
• 61394-92-1 2, 3-dioxoindoline-5-carbonitrile 

Relevant articles and documents

Facile synthesis of isatins by direct oxidation of indoles and 3-iodoindoles using NIS/IBX

A facile one-pot access to a broad range of isatins by direct oxidation of indoles using NIS/IBX reagent in DMSO at 25 °C in very good isolated yields is reported. It is shown by mechanistic investigations that a number of substituted indoles react rapidly with NIS in DMSO to produce intermediary 3-iodoindoles, which undergo oxidation subsequently to isatins with IBX.

HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES

Heteroaryl compounds as agrochemical fungicides Formula (I) The present invention relates to heteroaryl compounds of formula (I) or a compound in the form of a stereoisomer, an agriculturally acceptable salt, a tautomer, an isotopic form, a N-oxide, a S- oxide, a prodrug or mixture thereof. The present invention further relates to the use of a com- pound of formula (I). Furthermore, the present invention relates to methods for combating phy- topathogenic harmful fungi, which methods comprising the steps of treatment of the phytopatho- genic fungi, the plant orthe plant propagation material selected from seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants to be protected against fungal attack, stored materials or harvest, or alternatelythe locus or soil or soil substituents or surfaces therefrom, with at least one compound of formula (I).

Cu-catalyzed synthesis of tryptanthrin derivatives from substituted indoles

A concise method for the preparation of tryptanthrins from indoles via the copper-catalyzed aerobic oxidation is described. The reactions can be carried out under mild reaction conditions with varying functional group tolerance.